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Review

The burden of type 2 diabetes: strategies to prevent or delay onset

Pages 511-520 | Published online: 24 Dec 2022

Figures & data

Figure 1 Summary of the relative risk reduction (%) of new-onset type 2 diabetes in randomized, controlled clinical trials of prevention. Studies shown are the Da Qing IGT and Diabetes Study, which evaluated diet and exercise (CitationPan et al 1997); the Finnish Diabetes Prevention Study, which evaluated diet and exercise (CitationTuomilehto et al 2001); the Diabetes Prevention Program (DPP) studies, which evaluated diet and exercise or metformin (CitationKnowler et al 2002); the Study To Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM), which evaluated acarbose; Troglitazone in Prevention of Diabetes (TRIPOD), which evaluated Troglitazone; XENical in the Prevention of Diabetes in Obese Subjects (XENDOS), which evaluated the gastrointestinal lipase inhibitor orlistat (CitationTorgerson et al 2004); and a meta-analysis of 10 trials of RAS blockade with either ACE inhibitors or ARBs (CitationScheen 2004a). (See text for study details.)

Figure 1 Summary of the relative risk reduction (%) of new-onset type 2 diabetes in randomized, controlled clinical trials of prevention. Studies shown are the Da Qing IGT and Diabetes Study, which evaluated diet and exercise (CitationPan et al 1997); the Finnish Diabetes Prevention Study, which evaluated diet and exercise (CitationTuomilehto et al 2001); the Diabetes Prevention Program (DPP) studies, which evaluated diet and exercise or metformin (CitationKnowler et al 2002); the Study To Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM), which evaluated acarbose; Troglitazone in Prevention of Diabetes (TRIPOD), which evaluated Troglitazone; XENical in the Prevention of Diabetes in Obese Subjects (XENDOS), which evaluated the gastrointestinal lipase inhibitor orlistat (CitationTorgerson et al 2004); and a meta-analysis of 10 trials of RAS blockade with either ACE inhibitors or ARBs (CitationScheen 2004a). (See text for study details.)