Reduction of C-reactive protein and the use of anti-hypertensives

Figures & data

Figure 1 Scheme of angiotensin II-induced inflammation and vascular damage.

Abbreviations: Ang II, angiotensin II; EC, endothelial cell; ECM, extracellular matrix; ET-1, endothelin-1; ICAM, intercellular adhesion molecule; NAD(P)H oxidase, nicotinamide adenine dinucleotide phosphate oxidase; NO, nitric oxide; NF-κB, nuclear factor kappa B; ROS, reactive oxygen species; VCAM, vascular cell adhesion molecule; (-), inhibition or reduction.

Figure 2 Scheme of C-reactive protein-induced inflammation.

Abbreviations: Ang II, angiotensin II; AT₁R, angiotensin type 1 receptor; BP, blood pressure; CRP, C-reactive protein; ET-1, endothelin-1; ICAM, intercellular adhesion molecule; NAD(P)H oxidase, nicotinamide adenine dinucleotide phosphate oxidase; NO, nitric oxide; PAI-1, plasminogen activator inhibitor-1; ROS, reactive oxygen species; TPA, tissue plasminogen activator; VCAM, vascular cell adhesion molecule; vWF, von Willebrand factor; (-), reduction.