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Review

Clinical update on the therapeutic use of clopidogrel: treatment of acute ST-segment elevation myocardial infarction (STEMI)

, &
Pages 379-387 | Published online: 24 Dec 2022

Figures & data

Figure 1 Death, myocardial infarction or occlusion of infarct-related artery on angiography in the CLARITY randomized trial. Reproduced from CitationSabatine MS, Cannon CP, Gibson CM, et al. 2005a. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med, 352:1179–89.

Copyright © 2005 Massachusetts Medical Society.

Figure 1 Death, myocardial infarction or occlusion of infarct-related artery on angiography in the CLARITY randomized trial. Reproduced from CitationSabatine MS, Cannon CP, Gibson CM, et al. 2005a. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med, 352:1179–89.Copyright © 2005 Massachusetts Medical Society.

Figure 2 Effect of clopidogrel on death before first discharge from hospital in COMMIT. Reproduced from CitationChen ZM, Jiang LX, Chen YP, et al. 2005. Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction:randomised placebo-controlled trial. Lancet, 366:1607–21. Copyright © 2005, with permission from Elsevier.

Figure 2 Effect of clopidogrel on death before first discharge from hospital in COMMIT. Reproduced from CitationChen ZM, Jiang LX, Chen YP, et al. 2005. Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction:randomised placebo-controlled trial. Lancet, 366:1607–21. Copyright © 2005, with permission from Elsevier.

Figure 3 Effects of clopidogrel on primary end point, a composite of death, reinfarction, or stroke before first discharge from hospital in COMMIT Reproduced from CitationChen ZM, Jiang LX, Chen YP, et al. 2005. Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction:randomised placebo-controlled trial. Lancet, 366:1607–21. Copyright © 2005, with permission from Elsevier.

Figure 3 Effects of clopidogrel on primary end point, a composite of death, reinfarction, or stroke before first discharge from hospital in COMMIT Reproduced from CitationChen ZM, Jiang LX, Chen YP, et al. 2005. Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction:randomised placebo-controlled trial. Lancet, 366:1607–21. Copyright © 2005, with permission from Elsevier.

Table 1 Comparison of the CLARITY and COMMIT randomized clinical trials (CitationChen et al 2005; CitationSabatine et al 2005a)