Excess coronary artery disease risk in South Asian immigrants: Can dysfunctional high-density lipoprotein explain increased risk?

Figures & data

Figure 1 Age-standardized prevalence of metabolic syndrome defined by NCEP ATP II criteria.

Table 1 Dyslipidemias in South Asian immigrants relative to other populations (Anand et al 2000)

Factor	†South Asian	†European	†Chinese	†p
Total cholesterol (mg/dl)	211.77 (81.90)	184.86 (81.90)	183.69 (81.90)	0.0001
LDL (mg/dl)	128.70 (35.10)	123.63 (31.20)	122.46 (31.20)	0.03
HDL (mg/dl)	38.56 (11.70)	46.41 (11.70)	46.41 (11.70)	0.0001
Triglycerides (mg/dl)	174.44 (115.70)	145.96 (115.70)	158.42 (115.70)	0.005
Lipoprotein (a) (g/L)‡	0.0293 (0.018)	0.0259 (0.0119)	0.0259 (0.0119)	0.001

Abbreviations: LDL, low-density lipoprotein; HDL, high-density lipoprotein.

Notes: ^†mean (SD)

^‡Natural Log.

Figure 2 Model of bidirectional conversion of high-density lipoprotein from antiinflammatory (a) to proinflammatory (b). Copyright © 2004. Reproduced with permission from Fogelman AM. 2004. When good cholesterol goes bad. Nat Med, 10:902–3.

Abbreviation: Apo A-I, apolipoprotein A-I.

AnandSSYusufSVuksanV2000Differences in risk factors, atherosclerosis, and cardiovascular disease between ethnic groups in Canada: the Study of Health Assessment and Risk in Ethnic groups (SHARE)Lancet3562798411071182

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FogelmanAM2004When good cholesterol goes badNat Med10902315340411

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