Sleep restriction increases white blood cells, mainly neutrophil count, in young healthy men: A pilot study

Figures & data

Table 1 Inflammatory markers and lipid profiles (mean ± SD) at baseline and after the third night of sleep restriction

Variables	Baseline	3rd Restriction Night	Wilcoxon p values
WBC 10^3 cells/μl	5.79 ± 1.04	6.88 ± 1.31	0.03
Lymphocytes 10^3 cells/μl	2.06 ± 0.41	2.01 ± 0.31	1
Monocytes 10^3 cells/μl	0.51 ± 0.15	0.61 ± 0.17	0.20
Neutrophils 10^3 cells/μl	3.17 ± 0.69	4.24 ± 0.97	0.01
RBC 10^6 cells/μl	5.09 ± 0.34	5.19 ± 0.28	0.78
Fibrinogen mg/dl	2.84 ± 0.27	2.71 ± 0.12	0.46
Hs-CRP mg/dl	0.21 ± 0.24	0.20 ± 0.24	1
Cholesterol mg/dl	171.5 ± 17.64	163.24 ± 25.84	0.23
Triglycerides mg/dl	58.5 ± 17.52	68.0 ± 26.59	0.29
HDL-C mg/dl	47.5 ± 10.97	46.25 ± 10.95	0.53
LDL-C mg/dl	112.3 ± 19.47	103.4 ± 22.44	0.16
ApoA mg/dl	117.5 ± 15.63	120.13 ± 20.61	0.46
ApoB mg/dl	94.45 +12.07	89.52 ± 23.79	0.34

Abbreviations: WBC, white blood cells; RBC, red blood cells; Hs-CRP, high sensitivity C-reactive protein; LDL, low density lipoprotein; HDL, high density lipoprotein.

Notes: Conversion for lipids; Total cholesterol, HDL-C, LDL-C: 1mol/L = 38.67 mg/dl; Triglycerides: 1 mol/L = 88.57 mg/dl.

Table 2 Inflammatory markers and lipid profiles (mean ± SD) at baseline and after the third night of sleep without restriction. Control group

Variables	Baseline	3rd Night without Restriction	Wilcoxon p values
WBC 10^3 cells/μl	6.71 ± 0.43	6.88 ± 0.42	0.82
Lymphocytes 10^3 cells/μl	2.48 ± 0.41	2.47 ± 0.14	0.73
Monocytes 10^3 cells/μl	0.58 ± 0.03	0.53 ± 0.04	0.3
Neutrophils 10^3 cells/μl	3.40 ± 0.32	3.65 ± 0.35	0.1
RBC 10^6 cells/μl	5.31 ± 0.29	5.28 ± 0.33	0.68
Fibrinogen mg/dl	2.79 ± 0.13	2.86 ± 0.15	0.25
Hs-CRP mg/dl	0.13 ± 0.04	0.10 ± 0.02	0.25
Cholesterol mg/dl	163 ± 8.3	165 ± 8.8	0.65
Triglycerides mg/dl	68 ± 37	60 ± 29	0.54
HDL-C mg/dl	46.1 ± 2.5	45 ± 2.4	0.19
LDL-C mg/dl	103 ± 6.7	107 ± 7.9	0.49
ApoA mg/dl	124 ± 8	118 ± 8.7	0.17
ApoB mg/dl	79 ± 5.3	83 ± 5.5	0.42

Abbreviations: WBC, white blood cells; RBC, red blood cells; Hs-CRP, high sensitivity C-reactive protein; LDL, low density lipoprotein; HDL, high density lipoprotein.

Notes: Conversion for lipids; Total cholesterol, HDL-C, LDL-C: 1mol/L = 38.67 mg/dl; Triglycerides: 1 mol/L = 88.57 mg/dl.