Individual patient-data meta-analysis comparing clinical outcome in patients with ST-elevation myocardial infarction treated with percutaneous coronary intervention with or without prior thrombectomy. ATTEMPT study: A pooled Analysis of Trials on ThrombEctomy in acute Myocardial infarction based on individual PatienT data

Figures & data

Table 1 Key characteristics of the trials entered in the ATTEMPT study

Study	Design	Thrombectomy device	Number of patients SPT		Pre-coronary time limit (hours)	Longest published clinical FU
VAMPIRE^Citation19	Multicenter	TVAC	175	180	<24	In hospital
X-AMINE ST^Citation17	Multicenter	X-Sizer	101	100	<12	Six months
DEAR-MI (19)	Single center	Pronto	74	74	<12	In hospital
Antoniucci et al^Citation14	Single center	Angiojet	50	50	<6	30 days
REMEDIA^Citation16	Single center	Diver CE	50	49	<12	In hospital
Noel et al^Citation28	Single center	Export	26	24	<12	In hospital
Kaltoft et al^Citation20	Single center	Rescue	107	108	<12	30 days
De Luca et al^Citation21	Single center	Diver CE	38	38	<12	Six months
PIHRATE^Citation25	Multicenter	Diver CE	94	102	<6	Six months
EXPIRA^Citation26	Single center	Export	87	88	<12	Nine months
TAPAS trial^Citation24	Single center	Export	536	535	<12	One year
ATTEMPT study population	–	–	1338	1348	–	–

Abbreviations: FU, follow-up; NA, not available; PCI percutaneous coronary intervention; SP, standard PCI; T, thrombectomy device treatment.

Table 2 Key characteristics of the study population in the 11 trials entered in the ATTEMPT study

Study	Age (mean)	Diabetes (%)	IIb/IIIa inhibitors (%)	Failed TL (%)	Anterior MI¶(%)	Mean symptom-to balloon time (minutes)	Baseline TIMI flow 0–1 (%)
VAMPIRE^Citation19	63	26	0	0	51	291*	75
X-AMINE ST^Citation17	61	22	51	0	52	257	100
DEAR-MI^Citation18	59	18	100	0	47	130	78
Antoniucci et al^Citation14	65	17	98	0	40	249	78
REMEDIA^Citation16	60	21	69	38	45	280^Table Footnote§	88
Noel et al^Citation28	60	13	NA	34	44	282	NA
Kaltoft et al^Citation20	64	7	95	0	44	225	69
De Luca et al^Citation21	65	21	100	0	100	438	100
PIHRATE^Citation25	60	10	62	0	NA	200	100
EXPIRA^Citation26	66	17	75	0	100	390	100
TAPAS study^Citation24	63	12	92	0	43	187	57

Abbreviations: MI, myocardial infarction; TS, thrombolysis;

¶, in the studies with missing anterior MI rate patients with left anterior descending artery as culprit artery where considered to have anterior MI;

§, symptom to angiography time;

*, symptom to hospital admission time; NA, not available.

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