Effects of efforts to intensify management on blood pressure control among patients with type 2 diabetes mellitus and hypertension: A pilot study

Figures & data

Figure 1 Flowchart of study population.

Table 1 Intention-to-treat analyses

Variable	#	A		B		C		P-value
		(N = 17)		(N = 19)		(N = 18)
Systolic pressure at baseline	54	152.41	±8.09	148.26	±6.81	148.44	±7.72	0.19*
Diastolic pressure at baseline	54	73.35	±8.86	71.95	±14.19	73.5	±12.26	0.91*
Systolic pressure at six months	54	152.76	±11.91	147.05	±13.87	143.28	±13.64	0.11*
Diastolic pressure at six months	54	73.88	±12.04	74.05	±13.77	72	±12.33	0.87*
Systolic: difference from baseline	54	0.35	±15.04	−1.21	±11.08	−5.17	±11.23	0.41*
Diastolic: difference from baseline	54	0.53	±8.94	2.11	±6.90	−1.5	±10.25	0.46*
SBP ≤ 130 and DBP ≤ 80, No. (%)	54	1	−6%	2	(11%)	1	6%	0.81#

* Notes: One-way ANOVA, p-value;

# Pearson’s chi-squared, p-value.

Abbreviations: DBP, diastolic blood pressure; SBP, systolic blood pressure.

Table 3 Per protocol analyses (subjects who completed the study)

Variable	#	A		B		C		P-value
		(n = 5)		(n = 7)		(n = 12)
Systolic pressure at baseline	24	156	±11.66	145.43	±5.26	149.17	±6.98	0.09*
Diastolic pressure at baseline	24	78.8	±2.68	68.43	±11.60	73.92	±13.83	0.34*
Systolic pressure at six months	24	157.2	±20.73	142.14	±20.88	141.42	±15.31	0.26*
Diastolic pressure at six months	24	80.6	±15.66	74.14	±11.05	71.67	±13.93	0.48*
Systolic: difference from baseline	24	1.2	±30.06	−3.29	±18.98	−7.75	±13.15	0.67*
Diastolic: difference from baseline	24	1.8	±17.80	5.71	±10.90	−2.25	±12.67	0.46*

* Notes: One-way ANOVA, p-value;

# Pearson’s chi-squared p-value.

Table 2 Baseline demographics

	Total n = 410	No response n = 213	No participation n = 143	Participants n = 54	Completed study n = 24
Gender
Unknown	213 (52%)	212 (100%)	1 (1%)	0 (0%)	0 (0%)
Female	104 (25%)	N/A	76 (53%)	28 (52%)	10 (42%)
Male	93 (23%)	1 (0%)	66 (46%)	26 (48%) p = 0.87*	14 (58%) p = 0.18#
Age
Unknown	356 (87%)	213 (100%)	143 (100%)	0 (0%)	0 (0%)
Age ≤ 60	13 (3%)	N/A	0 (0%)	13 (24%)	4 (17%)
Age > 60	41 (10%)	N/A	0 (0%)	41 (76%)	20 (83%)
State
Unknown	1 (0%)	1 (0%)	0 (0%)	0 (0%)	0 (0%)
MN	400 (98%)	206 (97%)	141 (99%)	53 (98%)	24 (100%)
Others	9 (2%)	6 (3%)	2 (1%)	1 (2%) p = 0.85*	0 (0%) p = 0.37#
HBA1c> 7%
Unknown	356 (87%)	213 (100%)	143 (100%)
No	32 (8%)	N/A	N/A	32 (59%)	15 (63%)
Yes	22 (5%)	N/A	N/A	22 (41%)	9 (38%) p = 0.66#

* Notes: Pearson’s chi-squared (compare participant vs nonparticipant combined);

# Pearson’s chi-squared (compare completed vs noncompleted).

Abbreviations: