Lower LINE-1 Methylation in First-Episode Schizophrenia Patients with the History of Childhood Trauma

Błażej Misiak1 Department of Psychiatry, Wroclaw Medical University, 10 Pasteur Street, 50-367 Wroclaw, Poland;2 Department of Genetics, Wroclaw Medical University, 1 Marcinkowski Street, 50-368 Wroclaw, PolandCorrespondence[email protected]
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Elżbieta Szmida2 Department of Genetics, Wroclaw Medical University, 1 Marcinkowski Street, 50-368 Wroclaw, PolandView further author information

Paweł Karpiński2 Department of Genetics, Wroclaw Medical University, 1 Marcinkowski Street, 50-368 Wroclaw, PolandView further author information

Olga Loska3 Department of Professional Training in Clinical Chemistry, Wroclaw Medical University, 211A Borowska Street, 50-566 Wroclaw, PolandView further author information

Maria M Sąsiadek2 Department of Genetics, Wroclaw Medical University, 1 Marcinkowski Street, 50-368 Wroclaw, PolandView further author information

Dorota Frydecka1 Department of Psychiatry, Wroclaw Medical University, 10 Pasteur Street, 50-367 Wroclaw, PolandView further author information

Lower LINE-1 Methylation in First-Episode Schizophrenia Patients with the History of Childhood Trauma

Table 1. General characteristics of first-episode schizophrenia patients and healthy controls.

Table 2. Differences in LINE-1 methylation between first-episode schizophrenia patients and healthy controls with respect to the history of childhood trauma after co-varying for age, gender, cigarette smoking measures and one-carbon metabolism parameters.

Table 3. Prediction of LINE-1 methylation by childhood trauma.

Table 4. Prediction of BAGE methylation by childhood trauma.

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Lower LINE-1 Methylation in First-Episode Schizophrenia Patients with the History of Childhood Trauma

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Table 1. General characteristics of first-episode schizophrenia patients and healthy controls.

Table 2. Differences in LINE-1 methylation between first-episode schizophrenia patients and healthy controls with respect to the history of childhood trauma after co-varying for age, gender, cigarette smoking measures and one-carbon metabolism parameters.

Table 3. Prediction of LINE-1 methylation by childhood trauma.

Table 4. Prediction of BAGE methylation by childhood trauma.

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