Abstract
Leukemias are the most common types of hematological cancers in children, and negatively impact functional capacity. There is evidence in the literature that therapeutic exercises can have a positive impact on functions. The aim of this study is to evaluate functional capacity, muscle strength, fatigue and quality of life through the application of a protocol of therapeutic exercises during pediatric leukemia hospitalization. Children will be allocated into two groups: one will carry out a protocol of therapeutic exercises, while the other will undergo conventional respiratory physiotherapy. The protocol is approved by the ethics and research committee of the host institution (No. 5.439.594). Results will be disseminated through peer-reviewed journal articles and conferences.
Clinical trial registration: RBR-8sxnfyd (https://ensaiosclinicos.gov.br)
Author contributions
C Freire Carniel and R Raimundo were responsible for conceiving and designing the study. R Raimundo is the study coordinator. C Freire Carniel, B Rosin and B Cunha de Souza are responsible for data collection. C Freire Carniel, B Rosin and R Raimundo drafted the manuscript. All authors contributed to writing and approved this manuscript.
Acknowledgments
The authors thank Faculdade de Medicina do ABC for providing support.
Financial & competing interests disclosure
The Faculdade de Medicina do ABC provided C Freire Carniel with an academic scholarship and research support for a graduate study (Institutional Agreement No. 950392). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. The authors declare that there is no conflict of interest in this study.
No writing assistance was utilized in the production of this manuscript.
Ethical conduct of research
The authors state that they have obtained appropriate institutional review board approval or have followed the principles outlined in the Declaration of Helsinki for all human or animal experimental investigations. In addition, for investigations involving human subjects, informed consent has been obtained from the participants involved.