Abstract
HIV-1 routinely escapes from antiviral drug pressure unless a combination therapy is used. In cases where viral escape follows a reproducible route, one can sometimes use molecular drug-resistance information for improvement of the drug or the therapeutic strategy with the aim to prevent viral escape.
Financial & competing interests disclosure
Research in the Berkhout laboratory is supported by the AIDS Fonds (Amsterdam), NWO-Chemical Sciences (Top Grant) and ZonMw (Translational Gene Therapy Program). The author has no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.