Figures & data
(A & B) CT intravenous pyelogram (coronal and axial views) showing polypoid soft tissue mass at the lower aspect of the urinary bladder measuring 3.3 × 3.1 × 2.4 cm compatible with the biopsy-proven malignant melanoma.
![Figure 1. CT intravenous pyelogram (coronal and axial views) of polypoid urinary bladder mass. (A & B) CT intravenous pyelogram (coronal and axial views) showing polypoid soft tissue mass at the lower aspect of the urinary bladder measuring 3.3 × 3.1 × 2.4 cm compatible with the biopsy-proven malignant melanoma.](/cms/asset/d3312a26-bde9-45f3-a4f0-8ffdc622522c/immt_a_12367202_f0001.jpg)
![Figure 2. Gross image of 4.0 × 3.0 × 2.5 cm polypoid inferior bladder mass with proximal urethral involvement and multifocal melanosis.](/cms/asset/5ef4b31b-6a50-4f38-9bdf-dd77c92064e2/immt_a_12367202_f0002.jpg)
(A & B) Robotic-assisted laparoscopic radical cystourethrectomy showing sheets of highly atypical dyscohesive melanoma cells in the urinary bladder 10× (left), tumor cells demonstrate positivity for SOX10 (right).
![Figure 3. Robotic-assisted laparascopic cystourethrectomy of urinary bladder showing sheets of highly atypical melanoma cells. (A & B) Robotic-assisted laparoscopic radical cystourethrectomy showing sheets of highly atypical dyscohesive melanoma cells in the urinary bladder 10× (left), tumor cells demonstrate positivity for SOX10 (right).](/cms/asset/2d466a2a-788b-424e-9163-8112c14db9c6/immt_a_12367202_f0003.jpg)
(A & B) Robotic-assisted laparoscopic radical cystourethrectomy showing the pagetoid spread of melanoma to the urethra (left), tumor cells demonstrate positivity for SOX10 (right).
![Figure 4. Robotic-assisted laparascopic cystourethrectomy of urinary bladder showing pagetoid spread of melanoma cells. (A & B) Robotic-assisted laparoscopic radical cystourethrectomy showing the pagetoid spread of melanoma to the urethra (left), tumor cells demonstrate positivity for SOX10 (right).](/cms/asset/05e2cff0-e5fb-4f75-aa13-605cc66d3fc5/immt_a_12367202_f0004.jpg)
(A & B) Robotic-assisted laparoscopic radical cystourethrectomy showing primary malignant melanoma of the urinary bladder with melanoma in-situ (left), specimen stains positive for SOX 10 (right).
![Figure 5. Robotic-assisted laparascopic cystourethrectomy of urinary bladder showing melanoma in situ. (A & B) Robotic-assisted laparoscopic radical cystourethrectomy showing primary malignant melanoma of the urinary bladder with melanoma in-situ (left), specimen stains positive for SOX 10 (right).](/cms/asset/476c98a1-0b94-4f90-abed-75b12fc02f18/immt_a_12367202_f0005.jpg)
(A & B) MRI pelvis (coronal and axial views) showing nodular enhancing soft tissue mass at the posterior segment of the urethra and urinary bladder base measuring 1.7 × 1.5 × 0.9 cm compatible with the biopsy-proven malignant melanoma.
![Figure 6. MRI pelvis (coronal and axial views) of nodular enhancing urinary bladder mass. (A & B) MRI pelvis (coronal and axial views) showing nodular enhancing soft tissue mass at the posterior segment of the urethra and urinary bladder base measuring 1.7 × 1.5 × 0.9 cm compatible with the biopsy-proven malignant melanoma.](/cms/asset/63c7dc23-a896-4040-a81e-2e05d29fed34/immt_a_12367202_f0006.jpg)
(A & B) Radical cystourethrectomy showing atypical melanoma cells of the urinary bladder with pagetoid spread of melanoma to the distal urethral margin.5× (left), tumor cells demonstrate positivity for SOX10 (right).
![Figure 7. Radical cystourethrectomy showing pagetoid spread to the distal urethral margin. (A & B) Radical cystourethrectomy showing atypical melanoma cells of the urinary bladder with pagetoid spread of melanoma to the distal urethral margin.5× (left), tumor cells demonstrate positivity for SOX10 (right).](/cms/asset/eebd5f19-1307-4d77-b15c-069d80586b12/immt_a_12367202_f0007.jpg)
(A & B) Radical cystourethrectomy showing highly atypical epithelioid melanoma cells of the urinary bladder 40× (left), tumor cells demonstrate positivity for SOX10 (right).
![Figure 8. Radical cystourethrectomy showing highly atypical epithelioid melanoma cells. (A & B) Radical cystourethrectomy showing highly atypical epithelioid melanoma cells of the urinary bladder 40× (left), tumor cells demonstrate positivity for SOX10 (right).](/cms/asset/71c68201-aee4-4d9e-8dbc-bd7a9d5697e3/immt_a_12367202_f0008.jpg)
(A & B) Radical cystourethrectomy showing atypical melanoma cells in the urinary bladder diffusely involving the submucosa and muscularis propria with corresponding urothelium uninvolved 1× (left), tumor cells demonstrate positivity for SOX10 (right).
![Figure 9. Radical cystourethrectomy showing atypical melanoma cells. (A & B) Radical cystourethrectomy showing atypical melanoma cells in the urinary bladder diffusely involving the submucosa and muscularis propria with corresponding urothelium uninvolved 1× (left), tumor cells demonstrate positivity for SOX10 (right).](/cms/asset/f75dd64d-d343-4940-abf2-a8f9329c2f21/immt_a_12367202_f0009.jpg)