North Carolina’s Multi-Institutional Pharmacogenomics Efforts with the North Carolina Precision Health Collaborative

Abstract

The North Carolina Precision Health Collaborative is an interdisciplinary, public-private consortium of precision health experts who strategically align statewide resources and strengths to elevate precision health in the state and beyond. Pharmacogenomics (PGx) is a key area of focus for the North Carolina Precision Health Collaborative. Experts from Atrium Health’s Levine Cancer Institute, Duke University/Duke Health System, Mission Health and the University of North Carolina (UNC) at Chapel Hill/UNC Health System have collaborated since 2017 to implement strategic PGx initiatives, including basic sciences research, translational research and clinical implementation of germline testing into practice and policy. This institutional profile highlights major PGx programs and initiatives across these organizations and how the collaborative is working together to advance PGx science and implementation.

Keywords::

• genomics
• North Carolina
• pharmacogenomics
• precision health

Acknowledgments

The authors would like to acknowledge L Dressler for her efforts as a founder of the personalized medicine program at Mission Health. G Bell led personalized medicine efforts at Mission Health prior to and during the development of this manuscript; G Bell now works at Genome Medical, Inc.

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.