Abstract
Despite low prevalence in most populations, the Brugada syndrome has attracted considerable attention in recent years because of its propensity to cause sudden cardiac death in otherwise healthy young individuals, and because of pathophysiologic underpinnings that link it to other ‘ion channelopathies’ such as the congenital long-QT syndromes. The natural history of Brugada syndrome poses unique challenges to the management of children and adolescents diagnosed with the disorder, particularly among the substantial majority of pediatric patients who are entirely asymptomatic at presentation. This review will explore the current state of understanding of Brugada syndrome as it relates specifically to children and adolescents, and will provide an approach to management based on limited available data and existing consensus recommendations, which refer primarily to adult patients.
Financial & competing interests disclosure
The author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.