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ORIGINAL ARTICLE

Standardization of protein biomarker measurements: Is it feasible?

, &
Pages 27-33 | Published online: 01 Jun 2010

Figures & data

Figure 1. A: Results from value assignment data on ceruloplasmin. The transfer factors shown are the [CER]ERM-DA470k/IFCC/[CER]ERM-DA470. Different symbols represent results obtained with different methods. B: Table of results from commutability studies for ERM-DA470 for the six different methods (numbered 1 to 6) represented in the value assignment data. “1” means that the value for ERM-DA470 is within the 95 % prediction interval for patient data for the two methods, a “0” means it that the value for ERM-DA470 is outside the prediction interval.

Figure 1. A: Results from value assignment data on ceruloplasmin. The transfer factors shown are the [CER]ERM-DA470k/IFCC/[CER]ERM-DA470. Different symbols represent results obtained with different methods. B: Table of results from commutability studies for ERM-DA470 for the six different methods (numbered 1 to 6) represented in the value assignment data. “1” means that the value for ERM-DA470 is within the 95 % prediction interval for patient data for the two methods, a “0” means it that the value for ERM-DA470 is outside the prediction interval.

Figure 2. Results from value assignment measurements for CRP in ERM-DA470k/IFCC (▴) and for ERM-DA472/IFCC (♦). The transfer factors shown are [CRP]ERM–DA470k/IFCC/[CRP]ERM–DA470 and [CRP]ERM–DA472/IFCC/[CRP]ERM–DA470. The materials are lyophilised and liquid frozen, respectively. The plot shows the mean values of individual datasets and the standard deviation.

Figure 2. Results from value assignment measurements for CRP in ERM-DA470k/IFCC (▴) and for ERM-DA472/IFCC (♦). The transfer factors shown are [CRP]ERM–DA470k/IFCC/[CRP]ERM–DA470 and [CRP]ERM–DA472/IFCC/[CRP]ERM–DA470. The materials are lyophilised and liquid frozen, respectively. The plot shows the mean values of individual datasets and the standard deviation.

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