Figures & data
Figure 1. Schematic representation of the tumour vasculature and microenvironment and their role in the response to hyperthermia. The tumour vascular supply controls heat deposition. It also delivers oxygen and nutrients to the tumour, thus controlling the microenvironment, and cells that exist in areas where these are deficient are more sensitive to heat damage. Both the vasculature and microenvironment are also influenced by heat, but this is dependent on the temperature of the hyperthermia treatment.
Table I. List of various parameters of importance for heating and the different methods for imaging them. MR, magnetic resonance; DCE-MRI, dynamic contrast-enhanced magnetic resonance imaging; DSC-MRI, dynamic susceptibility contrast magnetic resonance imaging; BOLD, blood oxygenation level dependent; VSI, vessel size imaging; NIRS, near infrared spectroscopy; EPR, electron paramagnetic resonance; SPECT, single photon emission computed tomography; CAIX, carbonic anhydrase IX.
