Long-term survival data of triple modality treatment of stage IIB–III–IVA cervical cancer with the combination of radiotherapy, chemotherapy and hyperthermia – an update

Figures & data

Figure 1. Recurrence-free survival (all patients).

Figure 2. Overall survival (all patients).

Figure 3. Recurrence-free survival by country (all patients).

Figure 4. Overall survival by country (all patients).

Table I.  Stage information and survival of advanced cervical cancer patients in the Netherlands, Norway and USA treated with the combination of radiotherapy, chemotherapy and hyperthermia.

	Netherlands (95% CI)	Norway (95% CI)	USA (95% CI)	Total (95% CI)
No. of patients	36	19	13	68
FIGO stage
IB unresectable	–	–	3*	3
IIB	26	11	5	42
IIIB	9	7	5	21
IVA	1	1	–	2
Macroscopic para-aortic nodes	–	–	8	8
Five-year RFS	65.8%	57.4%	38.5%^†	57.5%
	(51.7–83.6)	(38.8–84.9)	(19.3–76.5)	(46.6–71)
Five-year OS	73.7%	57%	61.1%^‡	66.1%
	(60.2–90.1)	(38.3–84.8)	(37.3–100)	(55.1–79.3)

*Unresectable due to tumour-positive lymph nodes or parametrial involvement on preoperative imaging studies.

^†Three-year RFS.

^‡Three-year OS.