Adherence to guidelines in people with screen-detected type 2 diabetes, ADDITION, Denmark

Figures & data

Figure 1. Flow-chart of study population among 401 people with screen-detected type 2 diabetes in 54 general practices in Denmark 2001–2004 (in the former county of South Jutland only in 2004 and in the former county of Copenhagen only after 2002).

Table I. Treatment initiation¹ with an ACE inhibitor or an angiotensin-II receptor antagonist by lifestyle and health characteristics among 226 people with screen-detected type 2 diabetes in 54 general practices in Denmark 2001–2006.

	All		Treatment initiation (410 days)
Characteristics	No.	%^2	CIP^3 (95% CI)	CIP difference (95% CI)
At baseline
Smoking
Lifetime non-smoker	69	30.8	0.48 (0.37–0.60)	Ref
Stopped smoking	79	35.3	0.43 (0.33–0.55)	–0.05 (–0.21–0.11)
Current smoker	76	33.9	0.60 (0.47–0.73)	0.12 (–0.06–0.29)
BMI (kg/m^2)
< 25	25	11.1	0.44 (0.27–0.66)	Ref
25–29	89	39.4	0.46 (0.36–0.57)	0.02 (–0.21–0.24)
≥ 30	112	49.6	0.56 (0.45–0.66)	0.11 (–0.11–0.34)
Self-rated health(SF36)
≤ 25 percentile(52)	50	22.9	0.58 (0.45–0.72)	0.04 (–0.13–0.22)
25–75 percentile	114	52.3	0.54 (0.44–0.65)	Ref
≥ 75 percentile(87)	54	24.8	0.40 (0.28–0.54)	–0.14 (–0.31–0.03)
Mental
≤ 25 percentile(76)	57	26.0	0.58 (0.45–0.72)	0.09 (–0.10–0.28)
25–75 percentile	68	31.1	0.49 (0.37–0.63)	Ref
≥ 75 percentile(92)	94	42.9	0.47 (0.38–0.58)	–0.02 (–0.19–0.15)
Total cholesterol(mmol/l)
< 5	61	27.9	0.49 (0.37–0.63)	Ref
5–5.9	76	34.7	0.46 (0.36–0.58)	–0.03 (–0.21–0.15)
6–6.9	51	23.3	0.53 (0.39–0.67)	0.04 (–0.16–0.23)
7–	31	14.2	0.64 (0.42–0.86)	0.15 (–0.12–0.43)
HbA1c (%)
< 6	47	20.8	0.49 (0.36–0.65)	Ref
6–6.9	108	47.8	0.53 (0.43–0.63)	0.03 (–0.15–0.21)
7–7.9	36	15.9	0.44 (0.30–0.62)	–0.05 (–0.27–0.17)
8–	35	14.5	0.54 (0.34–0.76)	0.04 (–0.22–0.31)
Blood pressure (mmHg)
Systolic
< 140	81	35.8	0.36 (0.26–0.49)	Ref
≥ 140–159	81	35.8	0.49 (0.38–0.60)	0.12 (–0.04–0.28)
≥ 160–	64	28.3	0.72 (0.58–0.85)	0.36 (0.17–0.54)
Diastolic
< 90	138	61.1	0.40 (0.32–0.49)	Ref
≥ 90	88	38.4	0.66 (0.55–0.76)	0.25 (0.11–0.39)

¹410 days after exceeded thresholds. ²of completed information. Missing data 5%. ³cumulative initiation proportion.

Table II. Treatment initiation¹ with an ACE inhibitor or an angiotensin-II receptor antagonist by demographic and social characteristics among 226 people with screen-detected type 2 diabetes in 54 general practices in Denmark 2001–2006.

	All		Treatment initiation (410 days)
Characteristics	No.	%^2	CIP^3 (95% CI)	CIP difference (95% CI)
Gender
Male	117	51.8	0.55 (0.45–0.65)	Ref
Female	109	48.2	0.46 (0.37–0.56)	–0.09 (–0.23–0.05)
Age, years
40–54	40	17.7	0.36 (0.22–0.55)	Ref
55–69	186	82.3	0.54 (0.46–0.61)	0.18 (–0.01–0.36)
Cohabitant
No	52	23.2	0.53 (0.38–0.69)	Ref
Yes	172	76.8	0.49 (0.42–0.57)	–0.04 (–0.21–0.13)
Vocational training
None	60	29.3	0.59 (0.45–0.73)	Ref
1–3 years	93	45.4	0.45 (0.35–0.56)	–0.14 (–0.32–0.04)
> 3 years	52	25.4	0.42 (0.29–0.56)	–0.17 (–0.37–0.03)
Employed
No	103	46.6	0.53 (0.43–0.64)	Ref
Yes	118	53.4	0.48 (0.39–0.58)	–0.05 (–0.19–0.10)

Notes: ¹410 days after exceeded thresholds; ²of completed information. Missing data < 10%; ³cumulative initiation proportion.

Table III. Treatment initiation¹ with an ACE inhibitor or an angiotensin-II receptor antagonist by general practice characteristics among 226 people with screen-detected type 2 diabetes in 54 general practices in Denmark 2001–2006.

	All		Treatment initiation (410 days)
Characteristics	No.	%	CIP^2 (95% CI)	CIP difference (95% CI)
Type of practice
Multi	146	64.6	0.49 (0.41–0.58)	Ref
Solo	80	35.4	0.52 (0.42–0.64)	0.03 (–0.11–0.18)
GP's gender
Both sexes represented	102	45.1	0.45 (0.36–0.56)	Ref
Only female	21	9.3	0.48 (0.29–0.71)	0.03 (–0.21–0.27)
Only male	103	45.6	0.56 (0.46–0.67)	0.11 (–0.04–0.26)
GPs’ average age
< 50 years	114	50.4	0.51 (0.42–0.61)	Ref
≥ 50 years	112	49.6	0.50 (0.40–0.61)	–0.01 (–0.15–0.13)
Postcode registered
< 10,000 inhibitants	66	29.2	0.46 (0.34–0.61)	Ref
≥ 10,000 inhibitants	160	70.8	0.52 (0.44–0.61)	0.06 (–0.10–0.22)
Number of patients per GP
≤ 25 percentile(1241)	43	19.0	0.50 (0.36–0.66)	–0.04 (–0.22–0.14)
25–75 percentile	133	58.9	0.53 (0.44–0.63)	Ref
≥ 75 percentile(1707)	50	22.1	0.43 (0.30–0.58)	–0.11 (–0.28–0.06)

Notes: ¹410 days after exceeded thresholds; ²cumulative initiation proportion.

Figure 2. Time to initiate treatment with an ACE inhibitor or an angiotensin-II receptor antagonist among 226 people with screen-detected type 2 diabetes in 54 general practices in Denmark 2001–2006. Upper panel shows results independent of BP level. Middle panel shows results in relation to initial systolic BP and lower panel in relation to initial diastolic BP.