Badminton, rectal cancer and 25 kg weight gain during chemotherapy

Figures & data

Figure 1.  Body composition changes in our patient. While absolute fat free mass remained constant during time, the patient gained 20.9 kg of body fat over the course of the study. Relative body fat, in 2005, measured at 22.8%; this value nearly doubled to 42.5% by 2008.

Table I.  Differential diagnosis [2] and diagnostic workup

Obesity – list of differential diagnosis	Findings in our patient N.A.=not applicable (reference range)
Iatrogenic causes
Drugs and hormones	Valproate, Chemotherapy, Steroids
Diet	Unchanged
High fat diets	N.A.
Overeating	N.A.
Neuroendocrine obesities
Hypothyroidism	TSH 1.23 mU/l (0.2–3.5)
Hypothalamic obesity	N.A.
Seasonal affective disorder	N.A.
Cushing's syndrome	No, urine cortisol 180 nmol/d (28 – 220); ACTH 19 ng/l (5–35)
Polycystic ovary syndrome	No
Hypogonadism	Menopause LH 25.3 U/l (20–70); FSH 91.9 U/l (30–130); Estradiol < 0.09 nmol/l (<0.23); Progesterone < 0.4 nmol/l (<0.6) (ref. range given is for postmenopausal women)
Social and behavioural factors	No
Genetic obesity	No
Low birth weight	No
Enforced inactivity	YES

Uptodate, http://www.uptodateonline.com/online/content/image.do;jsessionid=CE23B6DBF597D2D26F26307CD4DE5295.0604?imageKey=endo_pix/etiolo1.htm&title=Etiology%20of%20obesity. accessed Nov 6, 2008.

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