The effect of ovarian dysfunction on bone mineral density in breast cancer patients 10 years after adjuvant chemotherapy

Figures & data

Figure 1. T-score (A) and percentual (B) BMD changes in the lumbar spine according to menstrual status.

Table I. Pretreatment characteristics of the patients according to menstrual status.

	Regular menses				Irregular menses				Amenorrhea
Characteristic	Mean	SD	No.	%	Mean	SD	No.	%	Mean	SD	No.	%
Patients, no.			4				16				9
Age, years	36				45				47
Range	28–44				39–50				41–52
Weight, kg	62.2	9.9			64.0	9.1			67.6	8.2
Height, cm	164.5	3.3			163.2	9.3			167	4.4
BMD, g/cm^2
Lumbar spine	1.07	0.15			1.01	0.16			1.01	0.13
Femoral neck	0.86	0.14			0.85	0.09			0.91	0.12
Total femoral area	0.99	0.15			0.98	0.09			1.00	0.11
T-score
Lumbar spine	0.24	1.32			−0.28	1.44			−0.35	1.14
Femoral neck	−0.32	1.36			−0.46	0.90			0.11	1.17
Total femoral area	−0.22	1.27			0.06	0.76			0.27	0.91
T-score classification
Lumbar spine
Normal			3	75%			11	69%			6	67%
Osteopenia			1	25%			5	31%			3	33%
Osteoporosis			0	0%			0	0%			0	0%
Femoral neck
Normal			3	75%			11	69%			7	78%
Osteopenia			1	25%			5	31%			2	22%
Osteoporosis			0	0%			0	0%			0	0%
Total femoral area
Normal			3	75%			14	88%			9	100%
Osteopenia			1	25%			2	12%			0	0%
Osteoporosis			0	0%			0	0%			0	0%

Figure 2. Changes in T-score classification (normal bone density, osteopenia and osteoporosis) of the lumbar spine BMD according to menstrual status.