Long-term functional and radiological pulmonary changes after radiation therapy for breast cancer

Figures & data

Table I. Baseline patients’ characteristics.

	n	Mean age years	Cardio vascular disease no.	Pulmonary disease no.	Adjuvant chemotherapy no.	Adjuvant tamoxifen no.	Smokers no.	Reduced functional level no.
Local RT	9	50	Slight*: 1 Severe**: 0	2 0	CMF: 9 FEC: 0	4	1	Slight°: 1 Severe°°: 0
Loco-regional RT Modrad.mastectomy	41	53	Slight: 8 Severe: 0	6 1	CMF: 16 FEC: 14	25	6	Slight: 5 Severe: 1
Loco-regional RT Part.mastectomy	20	57	Slight: 4 Severe: 0	2 0	CMF: 7 FEC: 9	11	4	Slight: 3 Severe: 0

*slight, hypertension or uncomplicated heart disease; **severe, cardiac failure; °slight, shortness of breath after 1 flight of stairs; °°severe, shortness of breath walking on flat ground.

Table II. Flowchart.

Figure 1. Box-and-whisker plots of the distribution of the percentage of the predicted VC values at baseline and at the long-term follow-up in all patients (n = 56); median 105% versus 92%; median-matched change −13%: p < 0.001.

Figure 2. (A) Box-and-whisker plots of radiological CT-scores at baseline (n = 29) and at long-term follow-up (n = 70). (B) Box-and-whisker plots of all patients who underwent both evaluations (n = 29) (n.s). (C) Box-and-whisker plots in patients who underwent LRRT and both evaluations (n = 23) (n.s).

Figure 3. Scatterplot of V₂₀ and CT scoring after 11 years of follow-up (n = 33).