Kinetics of inflammatory markers following cancer-related bowel and liver resection

Figures & data

Table I. Demographic data of patients and multiple organ dysfunction scores (MODS) in the two groups.

	Group A (n = 28)	Group B (n = 30)	P
Age (years)	53 (34–65)	63 (22–77)	NS
Gender (M/F)	19/11	21/7	NS
Duration of operation (min)	160 (90–270)	240 (60–440)	<0.001
Body weight (kg)	71 (54–85)	80 (63–118)	NS
Height (cm)	169 (154–183)	173 (160–194)	NS
MODS preoperatively (T0)	2 (1–3)	2 (1–3)	NS
MODS postoperatively (T1)	2 (1–3)	1 (1–3)	NS
MODS day 1 (T2)	2 (1–3)	1 (1–3)	NS
MODS day 2 (T3)	2 (1–3)	2 (1–3)	NS
MODS day 3 (T4)	2 (1–4)	3 (0–3)	NS

Our data are presented as median (interquartile range). For the statistical analyses the Mann-Whitney test was used. The duration of operation was significantly higher in group B.

Table II. Macrophage migration inhibitory factor (MIF) values in the two groups.

Groups	Group A	Group B	ANOVA P
MIF0	1137.87 ± 741.53	1462.94 ± 1276.49	NS
MIF1	4505.87 ± 551.72	1774.13 ± 1125.39	0.001
MIF2	1661.75 ± 869.88	1506.28 ± 1097.42	NS
MIF3	1558.50 ± 1113.55	1490.97 ± 1358.18	NS
MIF4	1302.33 ± 741.25	996.24 ± 913.85	NS

Values are means ± SD. For the statistical analyses the ANOVA test was used.

Figure 1. Serum MIF levels preoperatively (MIF0), immediately postoperatively (MIF1), and on the three consecutive days (MIF2, MIF3, MIF4). The data were plotted as a ‘box plot’. The minimum–maximum and interquartile ranges are shown on the figure. The difference in the two groups was verified by the Mann-Whitney U test. *P < 0.006.