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Case Reports

Oxygen free radical and antioxidant status in necrotizing soft tissue infection of the lower extremity; a report of two cases with opposite outcomes

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Pages 46-50 | Received 14 Sep 2012, Accepted 21 Sep 2012, Published online: 20 Nov 2012

Figures & data

Figure 1. Computed tomography of the right thigh of case 1. A circumferential gas pattern was observed.

Figure 1. Computed tomography of the right thigh of case 1. A circumferential gas pattern was observed.

Figure 2. The clinical course and changes in white blood cell count and C-reactive protein of case 1 (survival case). (HBO = hyperbaric oxygen therapy; POD = postoperative day).

Figure 2. The clinical course and changes in white blood cell count and C-reactive protein of case 1 (survival case). (HBO = hyperbaric oxygen therapy; POD = postoperative day).

Figure 3. Computed tomography of the left thigh of case 2. A circumferential abscess pattern was observed.

Figure 3. Computed tomography of the left thigh of case 2. A circumferential abscess pattern was observed.

Figure 4. The clinical course and changes in white blood cell count and C-reactive protein of case 2 (death case). (HBO = hyperbaric oxygen therapy; CHDF = continuous hemodiafiltration; POD = postoperative day).

Figure 4. The clinical course and changes in white blood cell count and C-reactive protein of case 2 (death case). (HBO = hyperbaric oxygen therapy; CHDF = continuous hemodiafiltration; POD = postoperative day).

Figure 5. Changes in serum d-ROMs and BAP. Serum d-ROM levels were increased in the patient who survived (case 1, open symbols) but decreased with time in the patient who died (case 2, closed symbols). Serum BAP levels remained within the normal range throughout the course of the disease in both cases. (Adm. = admission). Grey area = normal range

Figure 5. Changes in serum d-ROMs and BAP. Serum d-ROM levels were increased in the patient who survived (case 1, open symbols) but decreased with time in the patient who died (case 2, closed symbols). Serum BAP levels remained within the normal range throughout the course of the disease in both cases. (Adm. = admission). Grey area = normal range

Figure 6. Changes in serum IL-6 (inflammatory cytokine) and IL-10 (anti-inflammatory cytokine). Serum IL-6 and IL-10 were both high on admission in the patient who died (closed symbols); the IL-10 level remained high during hospitalization. (Adm. = admission).

Figure 6. Changes in serum IL-6 (inflammatory cytokine) and IL-10 (anti-inflammatory cytokine). Serum IL-6 and IL-10 were both high on admission in the patient who died (closed symbols); the IL-10 level remained high during hospitalization. (Adm. = admission).