Figures & data
Figure 1. Effects of CUMS exposure and ketamine administration on immobility time during FST and latency to feed during NSFT of rats. Data are presented as the mean ± SEM of 8 rats per group. *P < 0.05, ***P < 0.001, versus control, # P < 0.05, ## P < 0.01, ### P < 0.001, versus CUMS (saline). Ket = ketamine.
Figure 2. Effects of CUMS exposure and ketamine administration on the levels of IL-1β (A), IL-6 (B), and TNF-α (C) in the rat hippocampus. Levels of IL-1β at 0.5 and 1 h (A), IL-6 at 0.5, 1, 2, and 4 h (B), and TNF-α at 2 and 4 h (C) were reduced after ketamine treatment. Data are presented as the mean ± SEM of 8 rats per group. *P < 0.05, versus control, # P < 0.05, versus CUMS (saline). Ket = Ketamine.
Figure 3. Effects of CUMS exposure and ketamine administration on IDO levels (A) and the KYN/TRP ratio (B) in the rat hippocampus. IDO levels (A) and the KYN/TRP ratio (B) were reduced at 0.5, 1, 2, and 4 h after ketamine treatment. Data are presented as the mean ± SEM of 8 rats per group. *P < 0.05, versus control, ## P < 0.01, # P < 0.05, versus CUMS (saline). Ket = Ketamine.
