Figures & data
Figure 1. Genomic region of human chromosome 11 harbouring the MTNR1B gene locus and linkage disequilibrium (LD) data of representative single nucleotide polymorphisms (SNPs) within this region (HapMap data). The MTNR1B gene consists of 2 exons and spans 13,160 bases from nucleotide 92,342,437 to nucleotide 92,355,596. The locations of the genotyped representative SNPs are indicated by arrows. The HapMap minor allele frequencies (MAF) are given below the SNP numbers. The Haploview LD colour scheme ‘r-squared’ was chosen to visualize LD data. Within the diamonds, the r2 values are given. SNP rs8192552 (G24E) is not covered by the HapMap data and was added, therefore, on the right side of the diamonds. No linkage data are available for this SNP.
![Figure 1. Genomic region of human chromosome 11 harbouring the MTNR1B gene locus and linkage disequilibrium (LD) data of representative single nucleotide polymorphisms (SNPs) within this region (HapMap data). The MTNR1B gene consists of 2 exons and spans 13,160 bases from nucleotide 92,342,437 to nucleotide 92,355,596. The locations of the genotyped representative SNPs are indicated by arrows. The HapMap minor allele frequencies (MAF) are given below the SNP numbers. The Haploview LD colour scheme ‘r-squared’ was chosen to visualize LD data. Within the diamonds, the r2 values are given. SNP rs8192552 (G24E) is not covered by the HapMap data and was added, therefore, on the right side of the diamonds. No linkage data are available for this SNP.](/cms/asset/9c28cc8b-6366-4dc5-9c68-711ecd6ae59d/iann_a_502125_f0001_b.gif)
Table I. Associations of single nucleotide polymorphisms within or in proximity to the MTNR1B gene locus with prediabetes phenotypes and risk of type 2 diabetes.