Erratum

Figures & data

Figure 1. MetS as a multifaceted disease encompassing central obesity, atherogenic dyslipidemia, hypertension, and insulin resistance. Low antioxidant status can contribute to the development of hypertension and insulin resistance, while hypercholesterolemia, specifically high LDL-C, is a primary target for atherogenic dyslipidemia.

Table VI. Summary comparison of blood pressure-lowering mechanisms between lycopene and tomato extracts and prescription medications.

Hypertension Functional food and nutraceuticals		Prescription medication
Tomato extract and lycopene:		ACE inhibitor:
↑ Antioxidant defenses	}↓ Vasoconstriction	↓ Angiotensin II production
↑ Nitric oxide levels?		Angiotensin II receptor antagonist
↓ Peroxynitrate formation		Inhibits angiotensin II from binding to its receptor in vascular smooth muscle
		Calcium blockers:
		↓ Cardiac and arteriole muscle contraction
		β-Blockers:
		↓ Cardiac output
		↓ Renin release
		Thiazides:
		Diuretics
		↓ Sodium reabsorption