Figures & data
Figure 1. The (pro)renin receptor regulates the renin-angiotensin system by increasing the catalytic activity of (pro)renin and increasing angiotensin formation. (Pro)renin binding to the PRR also results in the activation of signalling cascades, resulting in the expression of inflammatory and fibrotic molecules (left panel). Additionally, PRR interacts with members of the Wnt receptor complex and contributes to the activity of the V-ATPase, thereby regulating the Wnt signal activation (right panel). See text for further details.
