The impact of serum homocysteine on intima-media thickness in normotensive, white-coat and sustained hypertensive adolescents

Figures & data

Table I. The most important confounding factors and results of laboratory tests.

	Normotensive (n = 59)	White coat hypertensives (n = 47)	Sustained hypertensives (n = 73)
Female/male	29/30	28/19	29/44
Age (years)	15.8 ± 0.6	16.3 ± 1.1	16.5 ± 1.0
Body weight (kg)	58.3 ± 11.5	64.06 ± 13.8	71.6 ± 15.5
Height (cm)	169.0 ± 9.2	170.5 ± 9.9	174.2 ± 8.3
BMI (kg/m^2)	20.2 ± 2.7	21.8 ± 3.5	23.4 ± 4.2
Systolic BP average	114.9 ± 10	138.3 ± 11.4	144.8 ± 11.1
MAP average	83.0 ± 8.4	101.1 ± 7.9	103.2 ± 6.4
Diastolic BP average	66.8 ± .9	82.5 ± 11.0	82.4 ± 8.3
Serum glucose (mmol/l)	5.3 ± 0.7	5.4 ± 0.7	5.6 ± 1.5
Serum cholesterol (mmol/l)	4.2 ± 0.7	4.3 ± 0.7	4.2 ± 0.8
HDL-cholesterol (mmol/l)	1.5 ± 0.2	1.5 ± 0.2	1.4 ± 0.3
LDL-cholesterol (mmol/l)	2.3 ± 0.5	2.4 ± 0.6	2.4 ± 0.7
Serum triglyceride (mmol/l)	0.86 ± 0.44	0.93 ± 0.45	1.08 ± 0.65

BMI, body mass index; BP, blood pressure; MAP, mean arterial pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein.

Figure 1. Relationship between serum homocysteine (µmol/l) and intima-media thickness (cm).

Figure 2. Comparison of serum homocysteine (µmol/l) in normotensive, white coat and sustained hypertensive adolescents. Means and standard deviations are shown. p-values after Bonferroni correction are presented.

Figure 3. Comparison of serum NOx concentrations (µmol/l) in normotensive, white coat hypertensive and sustained hypertensive adolescents. Means and standard deviations are shown. p-values after Bonferroni correction are presented.