Meta-analysis: A tool for clinical and experimental research in psychiatry

Figures & data

Table 1. Meta-analysis of case–control studies on the role of the COMT (catechol-O-methyltrasferase) val158/108Met polymorphism in suicidal behavior.

	Number of COMTval alleles		Number of COMTmet alleles
References	Cases	Controls	Cases	Controls	Odds ratio (95% CI)
Tovilla-Zárate (2011)	126	272	84	200	0.90 (0.65–1.26)
Lee (2011)	223	273	117	121	1.18 (0.86–1.61)
Perround (2010)	848	255	784	221	1.06 (0.86–1.30)
Zalsman (2008)	182	121	220	117	1.25 (0.90–1.72)
Rujescu (2003)	139	323	159	333	1.10 (0.84–1.95)
Liou (2001)	95	275	29	101	0.83 (0.51–1.33)
Russ (2000)	52	58	46	40	1.28 (0.72–2.25)
Ohara (1998)	11	175	13	95	2.17 (0.93–5.04)
Random effects	1676	1752	1452	1228	1.09 (0.97–1.23)

Fig. 1. Odds ratios and forest plots of all models in overall studies. C allele vs T allele.