Investigation of Histopathologic Changes in Pelviureteral Junction Obstruction

Figures & data

Table 1  Histopathologic evaluation of the pelviureteral junction in humans [median (min–max)]

Groups	WTPUJ (μm)	TMPUJ (μm)	UTPUJ (μm)	CTPUJ (μm)
Control	780.3 (498.3–1261.0)	317.2 (273.1–760.9)	49.4 (28.1–80.4)	99.3 (72.8–334.6)
PUJO	886.7 (481.8–1287.0)	277.3 (173.9–502.0)	65.0 (29.4–126.4)	375.1 (207.7–667.0)

*p = .008 when compared with control.

Abbreviations: WTPUJ = wall thickness of the pelviureteral junction, TMPUJ = tunica muscularis of the pelviureteral junction, UTPUJ = uroepithelium thickness of obstructed pelviureteral junction, CTPUJ = collagen thickness of the pelviureteral junction, PUJO = pelviureteral junction obstruction.

Figure 1.  Photomicrograph of C group showing the morphology of a normal pelviureteral junction (Tripple).

Figure 2.  Photomicrograph of PUJO group showing the morphology of thick collagen in an obstructed pelviureteral junction (Tripple).

Figure 3.  Photomicrograph of PUJO group showing the morphology of tunica muscularis in an obstructed pelviureteral junction (α SMA).

Figure 4.  Photomicrograph of PUJO group showing the morphology of uroepithelium in an obstructed pelviureteral junction (H&E).