Lipid Abnormalities and Oxidized LDL in Chronic Kidney Disease Patients on Hemodialysis and Peritoneal Dialysis

Figures & data

Figure 1. Comparison of oxLDL concentration in normal controls (NC), hemodialysis (HD), and peritoneal dialysis (PD) groups.

Note: p < 0.0001 in all groups versus NC.

Table 1. Demographic data in patients on hemodialysis (HD), peritoneal dialysis (PD), and in normal controls (NC).

		Dialysis patients
	NC (n = 21)	Total (n = 55)	HD (n = 31)	PD (n = 24)
Age (years)	49 ± 4	58 ± 3	57 ± 3	58 ± 3
Male/female	11/10	27/28	16/15	11/13
Body mass index (kg/m^2)	23.0 ± 1.0	23.6 ± 0.9	24.2 ± 0.9	23.2 ± 0.8
Duration of dialysis (months)	–	64 ± 12	72 ± 15	54 ± 8
Creatinine (mg/dL)	0.72 ± 0.04	9.05 ± 0.50*	8.89 ± 0.43^**	9.24 ± 0.69^**
Urea (mg/dL)	24 ± 4	149 ± 8*	174 ± 8^**	124 ± 8^**,***
Albumin (g/dL)	4.43 ± 0.40	3.74 ± 0.18	4.00 ± 0.39	3.46 ± 0.07

Note: *p < 0.0001 versus NC, ^**p < 0.001 versus NC, ^***p < 0.001 versus HD.

Table 2. Serum lipid profile in patients on hemodialysis (HD), peritoneal dialysis (PD), and in normal controls (NC).

		Dialysis patients
	NC (n = 21)	Total (n = 55)	HD (n = 31)	PD (n = 24)
Cholesterol (mg/dL)	175 ± 6	176 ± 5	161 ± 4	191 ± 7*
Triglycerides (mg/dL)	81 ± 7	153 ± 10^**	137 ± 9^***	169 ± 14^****
LDL-C (mg/dL)	105 ± 4	98 ± 6	93 ± 6	102 ± 7
HDL-C (mg/dL)	57 ± 3	41 ± 2^**	40 ± 2^****	42 ± 3^****
HDL2-C (mg/dL)	33 ± 2	30 ± 2	27 ± 2	32 ± 3
HDL3-C (mg/dL)	23 ± 1	11±0.5^**	11 ± 0.5^****	10 ± 1^****
Apo-A1 (mg/dL)	151 ± 5	137 ± 5	129 ± 5^***	145 ± 5
Apo-B (mg/dL)	65 ± 3	71 ± 4	61 ± 4	80 ± 4^***,*****
oxLDL (mg/L)	0.22 ± 0.05	1.92 ± 0.29^**	1.41 ± 0.45^**	2.43 ± 0.17^**

Note: *p < 0.001 versus HD, ^**p < 0.0001 versus NC, ^***p < 0.01 versus NC, ^****p < 0.001 versus NC, ^*****p < 0.05 versus HD.