The Effect of HES (130/0.4) Usage as the Priming Solution on Renal Function in Children Undergoing Cardiac Surgery

Figures & data

Table 1.  Demographic and clinical data of Groups I and II (mean ± SD).

	Group I (RL)	Group II (HES)
Age (year)	5.1 ± 3.7	3.9 ± 1.7
Gender (F/M)	7/5	6/6
Weight (kg)	16.2 ± 8.8	13.5 ± 4.5
Operation duration (min)	203.3 ± 57.3	214.5 ± 57.9
CPB duration (min)	73.8 ± 40.9	65.6 ± 29.2
Aortic clamp duration (min)	52.5 ± 36.2	42.3 ± 26.2
ICU duration (day)	3 ± 2.8	2.5 ± 2.2
Hospitalization duration (day)	5.9 ± 3.2	5 ± 2.3

Table 2.  β2-Microglobulin levels (mean ± SD) (ng/dL).

	Group I (RL)	Group II (HES)
T1	1395.9 ± 247.8	1669.9 ± 401.9
T2	1467.4 ± 250.3	1622.4 ± 406.4
T3	961.4 ± 181.1*	1137.7 ± 279.9*
T4	1224.2 ± 260.8	1500.2 ± 301.9
T5	1208.7 ± 265.5	1476.7 ± 381.8
T6	1285.3 ± 299.6	1569.4 ± 936.3
T7	1267.3 ± 316.7	1305.8 ± 293.2

Note: *p < 0.05 within the group, compared to (T1) period.

Table 3.  Cystatin C levels of the RL and HES groups (mean ± SD) (mg/L).

	Group I (RL)	Group II (HES)
T1	0.82 ± 0.19	1.01 ± 0.18
T2	0.91 ± 0.19	0.96 ± 0.21
T3	0.61 ± 0.12*	0.71 ± 0.11*
T4	0.67 ± 0.16*	0.82 ± 0.13*
T5	0.67 ± 0.16*	0.82 ± 0.12*
T6	0.84 ± 0.14	0.96 ± 0.21
T7	0.81 ± 0.16	0.95 ± 0.18

Note: *p < 0.05 within the group, compared to (T1) period.

Figure 1.  FENa levels in the RL and HES groups (%).

Figure 2.  Creatinine clearance levels in the RL and HES groups. Note: *p < 0.05 within the group, compared to (T1) period.

Table 4.  Urine albumin/creatinine ratios in patients (mean ± SD) (μg/mg).

	Group I (RL)	Group II (HES)
T1	33.5 ± 30.1	48.4 ± 76.1
T2	53.9 ± 69.8	51.2 ± 42.5
T3	95.6 ± 117.1*	75.7 ± 70.1
T4	127.6 ± 105.1*	163.3 ± 249.8*
T5	171.7 ± 189.9*	108.5 ± 84.1
T6	69.8 ± 124.7	37.9 ± 32.8
T7	33.4 ± 24.7	65.1 ± 93.3

Note: *p < 0.05 within the group, compared to (T1) period.

Table 5.  Fluid balance of Groups I and II (mean ± SD) (×10³/μL).

	Group I (RL)	Group II (HES)
Drainage (mL)	192.1 ± 109.1	236.6 ± 127.2
Urinary output (mL)	1642.5 ± 839.1	1176.2 ± 648.1
Total fluid (mL)	1795.8 ± 890.5	1488.3 ± 390.3
Erythrocyte susp (mL)	242.5 ± 218.5	159.5 ± 94.3
Fresh frozen plm (mL)	224.2 ± 167.4	210.4 ± 149.5

Table 6.  Neutrophil levels in the RL and HES groups (mean ± SD) (×10³/μL).

	Group I (RL)	Group II (HES)
T1	4.48 ± 2.64	3.88 ± 1.48
T5	8.5 ± 3.4*	9.4 ± 4.7*
T6	8.4 ± 1.8*	10.1 ± 4.2*
T7	8.4 ± 3.2*	7.9 ± 2.2*

Notes: All data are presented as mean ± SD.*p < 0.05.

Table 7.  ES and RL/HES amounts added into priming solution (mean ± SD) (mL).

Added amount (mL)	Group I (RL)	Group II (HES)
ES	216.67 ± 126.73	245.83 ± 75.25
RL/HES	391.417 ± 207.25	316.67 ± 86.164