Evaluation of the Process of Recycling and Renal Parenchymal Injury after ESWL with Metabolites Excreted in the Urine

Figures & data

Table 1.  The distribution of energy, frequency, shock, and time variables in patients who were performed ESWL.

n		First session	Second session	p-Value
Energy (kV)	Median (min–max)	18.50 (16–20)	18 (16–20)	0.617
Frequency	Median (min–max)	77.5 (70–90)	75 (70–90)	0.285
Shock waves	Median (min–max)	1975 (1500–2500)	1900 (1550–2300)	0.118
Time	Median (min–max)	45 (30–55)	45 (35–55)	0.763

Table 2.  The distribution of metabolites excreted by urine before and after the second session ESWL and binary comparisons of them.

	b1e	a1e	b2e	a2e	p-Value	Binary comparisons
Cit. median	102.5 (38–312)	78.5 (35–399)	97 (45–360)	63.5 (30–453)	<0.001	b1e–a1e p < 0.05
(min–max)						b1e–b2e p > 0.05
mg/L						b1e–a2e p < 0.001
						a1e–b2e p < 0.05
						a1e–a2e p > 0.05
						b2e–a2e p < 0.001
RBP median	73.5 (37–108)	91 (43–133)	77 (39–166)	106.5 (54–188)	<0.001	b1e–a1e p < 0.001
(min–max)						b1e–b2e p > 0.05
ug/mL						b1e–a2e p < 0.001
						a1e–b2e p < 0.05
						a1e–a2e p < 0.05
						b2e–a2e p < 0.001
NAG mean	17.17 ± 10.12	23.88 ± 11.45	21.63 ± 9.75	37.17 ± 15.78	<0.001	b1e–a1e p < 0.01
± SD						b1e–b2e p < 0.01
ng/mL						b1e–a2e p < 0.001
						a1e–b2e p > 0.05
						a1e–a2e p < 0.001
						b2e–a2e p < 0.001
Cre median	68.05 (38.15–93.72)	79.68 (46.24–25.36)	78.258 (45.66–138.92)	94.09 (68.31–204.13)	<0.001	b1e–a1e p < 0.001
(min–max)						b1e–b2e p < 0.05
mg/dL						b1e–a2e p < 0.001
						a1e–b2e p > 0.05
						a1e–a2e p < 0.05
						b2e–a2e p < 0.001
UrA mean ±	39.25 ± 13.50	36.10 ± 12.92	40.69 ± 11.25	33.55 ± 11.05	<0.001	b1e–a1e p > 0.05
SD mg/dL						b1e–b2e p > 0.05
						b1e–a2e p > 0.05
						a1e–b2e p < 0.01
						a1e–a2e p > 0.05
						b2e–a2e p < 0.001
Na mean ±	133.30 ± 23.45	120.70 ± 22.25	130.60 ± 19.85	106.75 ± 19.19	<0.001	b1e–a1e p < 0.001
SD mmol/L						b1e–b2e p > 0.05
						b1e–a2e p < 0.001
						a1e–b2e p < 0.001
						a1e–a2e p < 0.001
						b2e–a2e p < 0.001
K median	39.05 (18.99–73.25)	34.67 (15.53–65.45)	37.92 (19.79–68.67)	27.27 (14.08–57.81)	<0.001	b1e–a1e p < 0.001
(min–max)						b1e–b2e p > 0.05
mmol/L						b1e–a2e p < 0.001
						a1e–b2e p < 0.01
						a1e–a2e p > 0.05
						b2e–a2e p < 0.001
P median	25.14 (10.37–49.28)	31.55 (17.22–58.43)	29.50 (11.90–56.27)	43.72 (19.38–62.20)	<0.001	b1e–a1e p < 0.001
(min–max)						b1e–b2e p > 0.05
mg/dL						b1e–a2e p < 0.001
						a1e–b2e p < 0.05
						a1e–a2e p > 0.05
						b2e–a2e p < 0.001
Ca median (min–max) mmol/L	1.92 (0.84–2.89)	1.96 (0.82–2.61)	1.99 (1.12–2.78)	1.95 (1.12–2.78)	0.461
Cl mean ± SD mmol/L	140.60 ± 29.13	137.90 ± 21.09	137.95 ± 22.02	143.70 ± 20.88	0.276

Notes: b1e, before (B1E) the first session ESWL; a1e, after (A1E) the first session ESWL; b2e, before (B2E) the second session ESWL; a2e, after (A2E) the second session ESWL.