To study the effect of monosodium glutamate on histomorphometry of cortex of kidney in adult albino rats

Figures & data

Figure 1. Photomicrograph of kidney sections of the control group rats showing normal histology of (a) glomerulus and (b) renal tubule in the cortical region (H&E stain ×40).

Table 1. The percentage of abnormal glomeruli in total number of fields examined in control and study group for both H&E and PAS stained slides.

Abnormal glomeruli	Control group (%)	Study group (%)
H&E stain	10	34.4
PAS stain	8.04	66.4

Figure 2. Photomicrograph of kidney sections of rats of experimental group treated with 4 mg MSG/g body weight for 30 d (PAS stain ×40). (a) Abnormal glomerulus, (b) hypercellularity, (c) degenerated renal tubule, (d) cellular debris.

Table 2. The comparison of morphometry of controls and experimental group.

	Control group, mean ± SD	Study group, mean ± SD	p Value
Glomerulus
Area (µm^2)	0.016 ± 0.005	0.029 ± 0.001	0.067
Length (µm)	0.154 ± 0.021	0.224 ± 0.001	0.043
Width (µm)	0.134 ± 0.024	0.165 ± 0.007	0.222
Bowman’s capsule
Area (µm^2)	0.022 ± 0.004	0.047 ± 0.001	0.033
Length (µm)	0.190 ± 0.014	0.250 ± 0.023	0.091
Width (µm)	0.160 ± 0.014	0.212 ± 0.004	0.038
Bowman’s space
Area (µm^2)	0.006 ± 0.001	0.015 ± 0	0.012
Length (µm)	0.036 ± 0.007	0.052 ± 0.001	0.088
Width (µm)	0.026 ± 0.010	0.065 ± 0.005	0.039

The bold values indicate significant data.