Comparison of effects of isotonic sodium chloride with diltiazem in prevention of contrast-induced nephropathy

Figures & data

Table 1. Demographic characteristics, creatinine clearances and basal plasma creatinine levels of patients.

	1st group (NaCl)		2nd group (bicarbonate)		3rd group (NaCl + Dilt.)		Total
	n	%	n	%	n	%	n	%	χ^2	F	p
Male	13	39.4	9	27.3	11	33.3	33	100	1.61	–	0.44
Female	7	25.9	11	40.7	9	33.3	27	100		–
DM	8	38.1	4	19.0	9	42.9	21	100	3.10	–	0.21
HT	12	33.3	11	30.6	13	36.1	36	100	0.41	–	0.81
Smoking	12	40.0	9	30.0	9	30.0	30	100	1.20	–	0.54
Total	20	33.3	20	33.3	20	33.3	60	100	–	–
Basal Cre.	1.37 ± 0.21		1.39 ± 0.16		1.39 ± 0.16		–	–	–	2.10	0.13
Cre. C.	53 ± 17.21		47 ± 13.51		47 ± 13.51		–	–	–	2.28	0.11

Notes: NaCl, sodium chloride; Dilt, diltiazem; Basal cre, basal creatinine; Cre. C, creatinine clearance.

Table 2. Plasma creatinine levels before and after the contrast injection.

	Basal X + SD	2nd day X + SD	7th day X + SD	F	p
1st Group (NaCl) (n = 20)	1 1.37 ± 0.21	1.33 ± 0.49	1.34 ± 0.30	0.1	0.90
2nd Group (Bicarb.) (n = 20)	1 1.39 ± 0.16	1.30 ± 0.20	1.41 ± 0.35	1.7	0.20
3rd Group (NaCl + Dilt) (n = 20)	1 1.56 ± 0.49	1.41 ± 0.40	1.45 ± 0.50	2.36	0.12

Notes: SD, standard deviation; NaCl, sodium chloride; Bicarb, bicarbonate; Dilt, Diltiazem.

Figure 1. The change in the plasma creatinine levels after the contrast injection.