Health-related quality of life, depression and mortality in peritoneal dialysis patients in Turkey: seven-year experience of a center

Figures & data

Figure 1. Flow chart of patient selection for the study.

Table 1. Socio-demographic and clinical features of PD patients.

Parameters	Surviving PD patients (n = 18) (mean ± SD)	Deceased PD patients (n = 45) (mean ± SD)	p Value
Age	43.6 ± 14.6	56.6 ± 15.0	0.003
Gender (F/M)	9/9	25/20	0.780
PD duration (months)	19.0 ± 28.2	21.5 ± 20.5	0.170
Primary kidney disease	0.002
Diabetes	1 (5.6%)	22 (48.9%)
Hypertension	5 (27.8 %)	3 (6.7.%)
Chronic GN	2 (11.2 %)	3 (6.7%)
ADPKD	1 (5.6 %)	1 (2.2%)
Chronic pyelonephritis	2 (11.2 %)	1 (2.2%)
Amyloidosis	2 (11.2 %)	2 (4.4%)
Unknown etiologies	5 (27.8 %)	13 (28.9 %)
Occupational	0.066
Employed	1(5.6%)	1 (2.2%)
Unemployed	5 (27.8%)	3 (6.7%)
Retired	8 (44.4%)	19 (42.2%)
Housewife	4 (22.2%)	22 (48.9%)
Residual urine	0.047
Presence	15 (83.3%)	25 (55.6%)
Absence	3 (16.7%)	20 (44.4%)
Comorbidity	0.001
Grade 0	16 (88.9%)	16 (35.6%)
Grade 1	2 (11.1%)	28 (62.2%)
Grade 2	0 (0%)	1 (2.2%)
Diabetes mellitus	0.001
Presence	1 (5.6%)	22 (48.9 %)
Absence	17 (94.4%)	23 (51.1 %)
Salary status (TL/month)	355.3 ± 268.8	346.4 ± 201.0	0.933
Educational status	0.083
Illiterate	2 (11.1%)	10 (22.2%)
Primary school	14 (77.8%)	31 (68.9%)
High school	0 (0%)	3 (6.7%)
University	2 (11.1%)	3 (6.7%)
Marital status	0.243
Single	3 (16.7%)	2 (4.4%)
Married	13 (72.2%)	35 (77.8%)
Widow	2 (11.1%)	8 (17.8%)

Note: ADPKD, autosomal dominant polycystic kidney disease; GN, glomerulonephritis; TL, Turkish lira.

Table 2. Laboratory values of surviving and deceased PD patients.

Parameters	Surviving PD patients (n = 18) (mean ± SD)	Deceased PD patients (n = 45) (mean ± SD)	p Value
BMI (kg/m^2)	26.7 ± 4.8	26.7 ± 4.9	0.982
Hemoglobin (g/dL)	11.2 ± 2.0	11.5 ± 1.8	0.604
Serum urea (mg/dL)	80.0 ± 19.4	99.7 ± 30.90	0.011
Serum creatinine (mg/dL)	6.0 ± 2.0	6.7 ± 2.7	0.337
Kt/v	2.85 ± 0.4	2.4 ± 0.6	0.053
Albumin (g/dL)	4.1 ± 0.4	3.7 ± 0.4	0.002
LDL cholesterol (mg/dL)	109.1 ± 28.7	121.2 ± 34.7	0.195
HDL cholesterol (mg/dL)	41.7 ± 8.0	41.9 ± 8.2	0.934
Triglyceride (mg/dL)	170.2 ± 71.0	205.9 ± 96.2	0.148
Calcium (mg/dL)	9.0 ± 0.6	8.9 ± 0.9	0.846
Phosphorus (mg/dL)	4.2 ± 0.9	4.3 ± 1.1	0.515
iPTH (pg/mL)	456.5 ± 589.1	437.4 ± 410.5	0.721
CRP (mg/dL)	10.9 ± 11.7	13.8 ± 12.4	0.130

Note: iPTH, intact parathormone.

Table 3. HRQoL, BDI Scores of surviving and deceased PD patients.

Parameters	Surviving PD patients (n = 18) (mean ± SD)	Deceased PD patients (n = 45) (mean ± SD)	p Value
HRQoL parameters
Mental health	48.9 ± 19.4	45.2 ± 16.1	0.547
General health status	39.8 ± 18.9	30.6 ± 15.0	0.040
Vitality	38.6 ± 19.2	32.4 ± 32.4	0.248
Social functioning	68.1 ± 20.2	59.2 ± 21.6	0.130
Role-physical	43.1 ± 42.7	21.7 ± 35.6	0.045
Role-emotional	44.4 ± 45.7	17.0 ± 35.3	0.011
Bodily-pain	83.3 ± 18.3	74.2 ± 28.6	0.220
Physical functioning	81.7 ± 21.4	59.3 ± 26.1	<0.001
Total SF-36 score	56.0 ± 19.6	42.5 ± 18.1	0.005
PCS	62.0 ± 15.9	46.4 ± 20.2	0.004
MCS	50.0 ± 19.2	35.5 ± 17.7	0.029
Total BDI score	20.8 ± 8.0	19.5 ± 9.5	0.574
BDI cognitive	16.4 ± 6.6	15.2 ± 7.5	0.640
BDI somatic	4.4 ± 2.2	4.3 ± 2.7	0.632

Table 4. Independent predictors of mortality in PD patients.

Parameters	Relative risk of mortality	Confidential interval (CI 95%)	p Value
Presence of diabetes	2.942	1.539–5.623	<0.001
Albumin (decrease 1 g/dL)	0.263	0.123–0.563	0.001