Outcomes in renal transplant recipients with lupus nephritis: experience at a single center

Figures & data

Figure 1. Kaplan–Meier estimates of patient and graft survival in kidney transplant recipients with lupus nephritis.

Table 1. Demographic and clinical characteristics and outcomes of 18 renal transplant recipients with lupus nephritis, who received 22 kidney allografts.

Age at transplantation, (y)	33.7 ± 10 (18–59)
Sex: female/male, (n)	16/2
Recipient race:
Caucasian, n (%)	9 (50.0)
Afro-descendants, n (%)	2 (11.0)
Mixed, n (%)	7 (39.0)
Length of dialysis (mo)	59 ± 45 (1–144)
Hemodialysis/peritoneal, (n)	13/5
Anti-Hepatitis C virus (positive), n (%)	6 (33.3)
Transplant donor: deceased/living (n)	16/6
Donor age (y)	38.6 ± 16 (12–58)
Previous transplants:
None, n (%)	16 (88.0)
>One, n (%)	2 (11.0)
Delayed graft function, n (%)	12 (54.5)
Cold ischemia time (h) (deceased–donor)	18.4 ± 5 (9–26)
Received mycophenolate/azathioprine (n)	14/8
Follow-up time post-transplantation (mo)	97 ± 70
Episodes of acute rejection n (%)	4 (18.2)
Infections, n patients (%)	11 (61.1)
Cause of graft loss:
Chronic allograft nephropathy, n (%)	6 (27.3)
Vascular thrombosis of the graft, n (%)	2 (9.1)
Acute vascular rejection, n (%)	1 (4.5)
Allograft rupture, n (%)	1 (4.5)
Death (2 with functioning graft), n (%)	3 (16.6)

Notes: Continuous variables are presented as means ± SD. Categorical variables are presented as numbers and percentages.

Table 2. Comparison of graft and patient survival in kidney transplant recipients in various series.

		Graft survival (%)				Patient survival (%)
Reference	N	1	5	10 years	N	1	5	10 years
Moroni et al6	35	–	85	76	33		97	97
Ghafari et al9	23	–	–	69	23	–	–	83
Bunnapradist et al3	1170	89^A	68^A	–	1170	94^A	85^A	–
	789	94^B	78^B	–	789	98^B	92^B	–
Yu et al12	23	95	73	57	23	95	95	95
Lionaki et al10	26	88	67	38	26	92	77	77
Azevedo et al13	48	93	81	–	45	98	91	–
Oliveira et al14	14	93	91	86	14	96	95	94
Present study	22	91	82	68	18	100	100	90

Notes: A – Deceased donor; B – Living donor.

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