Figures & data
Table 1. CD2AP mRNA levels at different time.
Figure 1. Western blot band of CD2AP of control group, Ang II group and Losartan group at different time points. (a): The control, (b): AngII, (c): Losartan.
![Figure 1. Western blot band of CD2AP of control group, Ang II group and Losartan group at different time points. (a): The control, (b): AngII, (c): Losartan.](/cms/asset/ce740429-2b98-40aa-b271-ac08e75c8450/irnf_a_934177_f0001_b.jpg)
Table 2. CD2AP protein levels at different time.
Figure 2. The percentage of apoptosis measured by Annexin-V FITC and PI staining. PI and Annexin V apoptosis kit by double staining was used to detect the apoptosis rate and subjected to flow cytometric analysis, in which X axis is Annexin V(+) and Y axis is PI (+), Q1 is PI (+), Annexin (−V); Q2 is PI (+), Annexin (+V), the late apoptosis or dead cells; Q3 is PI (−), Annexin V (−), the normal living cell; Q4 is Annexin V (+), PI (−), the early apoptosis cells. Losartan prevents Ang II-induced apoptosis. The percentage of apoptotic cells, measured by Annexin-V FITC and PI staining increased at 24 h in the cells that were exposed to Ang II without Losartan, whereas cells that were treated with Losartan were resistant to Ang II-induced apoptosis. *p < 0.05 versus Losartan (–) Ang II (+).
![Figure 2. The percentage of apoptosis measured by Annexin-V FITC and PI staining. PI and Annexin V apoptosis kit by double staining was used to detect the apoptosis rate and subjected to flow cytometric analysis, in which X axis is Annexin V(+) and Y axis is PI (+), Q1 is PI (+), Annexin (−V); Q2 is PI (+), Annexin (+V), the late apoptosis or dead cells; Q3 is PI (−), Annexin V (−), the normal living cell; Q4 is Annexin V (+), PI (−), the early apoptosis cells. Losartan prevents Ang II-induced apoptosis. The percentage of apoptotic cells, measured by Annexin-V FITC and PI staining increased at 24 h in the cells that were exposed to Ang II without Losartan, whereas cells that were treated with Losartan were resistant to Ang II-induced apoptosis. *p < 0.05 versus Losartan (–) Ang II (+).](/cms/asset/da678cef-c69f-4718-8421-99a23bb210f6/irnf_a_934177_f0002_b.jpg)