Evaluation of relationship between sexual functions, depression and quality of life in patients with chronic kidney disease at predialysis stage

Figures & data

Table 1. Comparison of laboratory data of male patients and the control group.

	Patients group (n = 26)	Control group (n = 20)
	Mean ± SD	Mean ± SD	p
BUN (mg/dL)	48.35 ± 40.35	14.4 ± 3.36	0.001
Creatinine (mg/dL)	2.45 ± 1.38	0.91 ± 0.14	0.0001
Uric acid (mg/dL)	6.82 ± 1.33	5.6 ± 1.5	0.008
Total protein (g/dL)	7.48 ± 0.57	7.3 ± 0.39	0.19
Albumin (g/dL)	4.29 ± 0.48	4.72 ± 0.2	0.001
Hematocrit (%)	40.49 ± 4.37	44.3 ± 3.13	0.001
PTH	135.73 ± 133.4	46.4 ± 16.2	0.005
CRP (mg/L)	10.2 ± 11.3	4.0 ± 2.5	0.02
ESR (mm/saat)	21.46 ± 16.6	14.7 ± 7.7	0.1
Testosterone (ng/mL)	4.16 ± 1.26	4.43 ± 1.66	0.44
DHEA-S (µg/dL)	166.06 ± 120	142.49 ± 66.5	0.4
Estrogen (pg/mL)	35.7 ± 10	37.8 ± 20.7	0.68
TSH (µIU/mL)	1.65 ± 1.27	1.86 ± 1.15	0.56
FSH (IU/L)	8.31 ± 6.44	4.74 ± 2.08	0.02
LH (IU/L)	8.44 ± 4.8	5.07 ± 3.57	0.009
Prolactin (ng/mL)	10.03 ± 3.68	5.96 ± 2.20	0.0001
Calcium (mg/dL)	8.8 ± 9.1	8.9 ± 6.1	0.25
Phosphorus (mg/dL)	3.5 ± 1.4	3.2 ± 0.5	0.38

Table 2. Laboratory data of female patients and controls.

	Patients group (n = 26)	Control group (n = 20)
	Mean ± SD	Mean ± SD	p
BUN (mg/dL)	4.27 ± 26.7	12.7 ± 2.65	0.0001
Creatinine (mg/dL)	2.44 ± 1.29	0.67 ± 0.09	0.0001
Uric acid (mg/dL)	6.16 ± 1.75	4.4 ± 0.81	0.0001
Total protein (g/dL)	7.42 ± 0.52	7.28 ± 0.30	0.25
Albumin (g/dL)	4.25 ± 0.35	4.4 ± 0.25	0.02
Hematocrit (%)	34.5 ± 3.4	38.7 ± 2.68	0.0001
PTH	190.83 ± 136.34	54 ± 28	0.0001
CRP (mg/L)	9.06 ± 14.7	5.3 ± 5.6	0.002
ESR (mm/saat)	33 ± 15	23 ± 13	0.25
Testosterone (ng/dL)	0.24 ± 0.30	0.20 ± 0.09	0.51
DHEA-S (µg/dL)	105 ± 100	117 ± 71	0.61
Estrogen (pg/mL)	27.79 ± 28.1	34,4 ± 28.9	0.43
TSH (µIU/mL)	2.38 ± 1.43	1.41 ± 0.7	0.005
FSH (IU/L)	85.1 ± 41.9	73.7 ± 32.5	0.01
LH (IU/L)	50.06 ± 49	21.29 ± 13.9	0.007
Prolactin (ng/mL)	20.4 ± 19.9	10.2 ± 6.7	0.01
Phosphorus (mg/dL)	3.73 ± 0.59	3.37 ± 0.44	0.02
Calcium (mg/dL)	9.1 ± 0.6	9.1 ± 0.29	0.6

Table 3. Quality of life and depression scores of male patients and controls.

	Patient group (n = 26)	Control group (n = 20)
	Mean ± SD	Mean ± SD	p
Age (years)	52.6 ± 7.1	51.3 ± 5.7	0.51
Physical function score	51.15 ± 21.4	81.5 ± 10.14	0.0001
Physical role score	50.96 ± 37	72.5 ± 22.79	0.03
Pain score	67 ± 25	74.5 ± 11.9	0.24
General health score	43.2 ± 15.2	73 ± 5	0.0001
Vitality score	61 ± 23	83.75 ± 6	0.0001
Socail function score	68.27 ± 24.81	93.75 ± 7.5	0.0001
Emotional role score	45.7 ± 27.64	74.65 ± 24	0.001
Mental health score	74 ± 20.46	77 ± 10	0.59
ED score	18.15 ± 5.75	16.9 ± 9.7	0.62
BDI score	15 ± 11	14 ± 10	0.55

Table 4. Quality of life and depression scores of female patients and controls.

	Patient group (n = 27)	Control group (n = 20)
	Mean ± SD	Mean ± SD	p
Age (years)	49.1 ± 9.87	48.3 ± 7.22	0.65
Physical function score	46.11 ± 17.96	85.25 ± 11.9	0.0001
Physical role score	48.4 ± 37.4	77.5 ± 24.1	0.002
Pain score	60 ± 26	74 ± 14.2	0.001
General health score	36.4 ± 17.1	73.4 ± 5.2	0.0001
Vitality score	52 ± 24	86 ± 5.9	0.0001
Social function score	67.6 ± 25.3	93.75 ± 7.5	0.0001
Emotional role score	47.6 ± 26.6	76.3 ± .22.1	0.001
Mental health score	66.9 ± 22.12	77 ± 10.6	0.002
BDI score	17 ± 11	10 ± 7	0.036

Table 5. Comparison of female sexual function indexes and components.

	Patients group (n = 26)	Control group (n = 20)
	Mean ± SD	Mean ± SD	p
FSFI total score	20.15 ± 4.23	27.3 ± 1.99	0.0001
Sexual desire score	4.5 ± 1.1	4.62 ± 0.91	0.01
Libido score	3.2 ± 1.5	4.3 ± 0.6	0.03
Lubrication score	2.93 ± 1.91	4.49 ± 0.65	0.0001
Sexual satisfaction score	2.6 ± 1.8	4.3 ± 0.6	0.0001
Orgasm score	3.14 ± 1.26	4.12 ± 0.62	0.0001
Pain score	3.10 ± 1.7	5.5 ± 0.7	0.0001