Effect of arteriovenous fistula and usage of arm with fistula on bone mineral density in hemodialysis patients

Figures & data

Table 1. Comparisons of bone mineral density scores of hemodialysis patients >51 and <50 years of age with age-matched controls.

	t Score of hemodialysis patients >51 years old (n = 63)	t Score of control patients >51 years old (n = 30)	p Value	z Score of hemodialysis patients <50 years old (n = 30)	z Score of control patients <50 years old (n = 30)	p Value
Lumbar 1–4	−1.8 ± 1.65	−1.13 ± 1.65-	0.14	−1.07 ± 1.64	0.08 ± 1.23	0.009
Femur neck	−1.56 ± 1.16	−0.58 ± 0.91	0.001	−0.35 ± 1.44	0.6 ± 0.98	0.003
Total femur	−1.08 ± 1.26	−0.10 ± 0.98	0.001	−0.60 ± 1.61	0.78 ± 0.84	0.001

Table 2. Comparisons of bone mineral density scores of arms with fistula and without fistula in dialysis patients  >51 and  <50 years of age.

	Arm with fistula in patients >51 years old (n = 63)	Arm without fistula in patients >51 years old (n = 63)	p Value	Arm with fistula in patients <50 years old (n = 33)	Arm without fistula in patients <50 years old (n = 33)	p Value
1/3 distal radius BMD g/cm^2	0.57 ± 0.14	0.59 ± 0.14	0.07	0.60 ± 0.12	0.61 ± 0.11	0.53
Total Radius BMD (g/cm^2)	0.47 ± 0.11	0.48 ± 0.11	0.03	0.50 ± 0.09	0.51 ± 0.09	0.02

Table 3. Comparison of arm with fistula of hemodialysis patients >51 years old with non-dominant arm of controls and comparison of their arm without fistula with dominant arm of healthy controls.

	Arm with fistula in patients >51 years old (n = 63)	Non-dominant arm in control subject >51 years old (n = 30)	p Value	Arm without fistula in patients >51 years old (n = 63)	Dominant arm in control subject >51 years old (n = 30)	p Value
1/3 distal radius BMD g/cm^2	0.57 ± 0.14	0.613 ± 0.11	0.20	0.59 ± 0.14	0.615 ± 0.13	0.3
Total radius BMD (g/cm^2)	0.47 ± 0.11	0.534 ± 0.10	0.01	0.48 ± 0.11	0.54 ± 0.10	0.02

Table 4. Comparison of arm with fistula of hemodialysis patients <50 years old with non-dominant arm of controls and comparison of their arm without fistula with dominant arm of controls.

	Arm with fistula in patients <50 years old (n = 33)	Non-dominant arm in control subject <50 years old (n = 30)	p Value	Arm without fistula in patients <50 years old (n = 33)	Dominant arm in control subject <50 years old (n = 30)	p Value
1/3 distal radius BMD g/cm^2	0.60 ± 0.12	0.722 ± 0.08	0.001	0.61 ± 0.11	0.73 ± 0.07	0.001
Total radius BMD (g/cm^2)	0.50 ± 0.09	0.624 ± 0.07	0.001	0.51 ± 0.09	0.591 ± 0.21	0.05

Table 5. Comparison of distal radius BMD of arm with fistula of hemodialysis patients >51 years old with non-dominant arm of controls and comparison of their arm without fistula with dominant arm of controls according to fistula localization.

	Patient group arm with fistula	Control group non-dominant arm	p Value	Patient group arm without fistula	Control group dominant arm	p Value
Patient group >51 years old with radial fistula (n = 53)
1/3 distal radius BMD g/cm^2	0.582 ± 0.14	0.613 ± 0.11	0.001	0.596 ± 0.13	0.615 ± 0.13	0.01
Total radius BMD (g/cm^2)	0.473 ± 0.11	0.534 ± 0.10	0.001	0.486 ± 0.11	0.54 ± 0.10	0.07
Patient group >51 years old with brachial fistula (n = 10)
1/3 distal radius BMD g/cm^2	0.529 ± 0.14	0.613 ± 0.11	0.09	0.529 ± 0.17	0.615 ± 0.13	0.15
Total radius BMD (g/cm^2)	0.467 ± 0.11	0.534 ± 0.10	0.13	0.475 ± 0.11	0.54 ± 0.10	0.11

Table 6. Comparison of distal radius BMD of arm with fistula of hemodialysis patients <50 years old with non-dominant arm of controls and comparison of their arm without fistula with dominant arm of controls according to fistula localization.

	Patient group arm with fistula	Control group non-dominant arm	p Value	Patient group arm without fistula	Control group dominant arm	p Value
Patient group <50 years old with radial fistula (n = 28)
1/3 distal radius BMD g/cm^2	0.616 ± 0.12	0.722 ± 0.08	0.001	0.613 ± 0.11	0.73 ± 0.07	0.001
Total radius BMD (g/cm^2)	0.499 ± 0.009	0.624 ± 0.07	0.001	0.511 ± 0.009	0.591 ± 0.21	0.07
Patient group <50 years old with brachial fistula (n = 5)
1/3 distal radius BMD g/cm^2	0.573 ± 0.14	0.722 ± 0.08	0.001	0.60 ± 0.6	0.73 ± 0.07	0.003
Total radius BMD (g/cm^2)	0.480 ± 0.12	0.624 ± 0.07	0.001	0.494 ± 0.13	0.591 ± 0.21	0.31

Table 7. Correlation of distal radius BMD scores of whole group with usage of the arm, age, duration of dialysis and fistula (usage of the arm by Likert scale).

	Usage of the arm by Likert scale		Age (year)		Duration of dialysis (months)		Duration of fistula (months)
	r	p	r	p	r	p	r	p
	1/3 distal radius BMD g/cm^2	0.303	0.003	−0.313	0.01	−0.07	0.37	−0.146	0.25
Total radius BMD (g/cm^2)	0.246	0.001	−0.301	0.01	−0.258	0.04	−0.164	0.2