724
Views
4
CrossRef citations to date
0
Altmetric
Letter to the Editor

Posterior Necrotizing Scleritis Presenting as Sectoral Chorioretinitis

, MD, PhD, , MD, , MD, DsC & , MD, MPH
Pages 412-415 | Received 11 Nov 2013, Accepted 17 Feb 2014, Published online: 21 Mar 2014

Figures & data

FIGURE 1. (A) Fundus photography demonstrating superotemporal area of chorioretinitis. There is a leading edge of inflammatory infiltrate with atrophy and scarring anterior to it. (B) B-scan ultrasound shows thickening of the retina and choroid. (C) Two months after her initial presentation, the area of retinitis has expanded. Note that the bifurcation of the vessels indicated by the arrow was not engulfed by the lesion in . (D) T1 post contrast fat-saturated MRI images demonstrate increased enhancement of the posterior sclera in the left eye (arrow). (E) Hematoxylin and eosin, 100× photomicrograph demonstrating granulomatous scleral inflammation. The lesion has a focal area of necrosis containing neutrophils surrounded by giant cells and epithelioid cells. (F) Hematoxylin and eosin, 200× photomicrograph shows focal area of necrosis with neutrophils. (G) Chromagranin diaminobenzine reaction, 100× photomicrograph stain for CD68 demonstrates positivity for histiocytes in the region surrounding the focal necrosis. (H) Postoperative fundus photography showing the healed biopsy site and no further progression of the chorioretinitis.

FIGURE 1. (A) Fundus photography demonstrating superotemporal area of chorioretinitis. There is a leading edge of inflammatory infiltrate with atrophy and scarring anterior to it. (B) B-scan ultrasound shows thickening of the retina and choroid. (C) Two months after her initial presentation, the area of retinitis has expanded. Note that the bifurcation of the vessels indicated by the arrow was not engulfed by the lesion in Figure 1A. (D) T1 post contrast fat-saturated MRI images demonstrate increased enhancement of the posterior sclera in the left eye (arrow). (E) Hematoxylin and eosin, 100× photomicrograph demonstrating granulomatous scleral inflammation. The lesion has a focal area of necrosis containing neutrophils surrounded by giant cells and epithelioid cells. (F) Hematoxylin and eosin, 200× photomicrograph shows focal area of necrosis with neutrophils. (G) Chromagranin diaminobenzine reaction, 100× photomicrograph stain for CD68 demonstrates positivity for histiocytes in the region surrounding the focal necrosis. (H) Postoperative fundus photography showing the healed biopsy site and no further progression of the chorioretinitis.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.