Release of pro-coagulant microparticles after moderate endurance exercise

Figures & data

Table I.  Time-dependent changes in the numbers of blood cells and circulating MP after physical exercise. Data are given as mean ± SD. ANOVA for repeated measurements was used to test for significant time-dependent changes; t-test for paired samples was applied to test for significant effects of exercise in comparison to basal values (rest). ns, not significant; § p ≤ 0.05.

Abosolute counts/µl	Rest	Post	45 min post	2 h post	ANOVA
White blood cells (*10^3)	5 ± 1	9 ± 3 §	11 ± 3 §	11 ± 2 §	p < 0.01
Platelets (*10^3)	238 ± 44	288 ± 51 §	244 ± 44	242 ± 40	p < 0.01
Annexin positive particles	3290 ± 1085	5990 ± 2334 §	8394 ± 3849 §	7045 ± 2976 §	p < 0.01
PMP	970 ± 473	1596 ± 779 §	2671 ± 1314 §	2184 ± 1592 §	p < 0.01
EMP	394 ± 212	440 ± 246	440 ± 231	440 ± 242	ns
MMP	33 ± 23	44 ± 26	45 ± 29	42 ± 27	ns

Figure 1. Functional activity tests at rest, immediately post-, 45 min post-, 2 h post exercise. A: MP pro-coagulant activity given as concentration of negatively charged phospholipids (nM). B: Maximum velocity (value*10⁻²) of fibrin formation (Δ optical density/time); § p ≤ 0.05 for differences to rest (t-test).