Neuropattern: A new translational tool to detect and treat stress pathology. II. The Teltow study

Figures & data

Figure 1.  Diagram of the study design. Flow charts are shown for the experimental and control groups. Missing = participants with missing data for follow-up. SCL-90-R, symptom checklist-90-R; SF-12, short form health questionnaire.

Table I.  Sample characteristics.

	Control group (n = 50)	Experimental group (n = 51)	p
Age: M (SD)	46.86 (9.43)	46.57 (8.72)	0.87
Sex (n; male:female)	12:39	15:35	0.51
Level of education (n)			0.61
Special education school	1	0
Mid-level secondary school	32	29
High-school graduate	15	17
College graduate	2	3
Duration of hospitalization in days: M (SD)	49 (11.26)	46.14 (9.19)	0.16
Application for a pension (n)	4	5	0.51
Health and well-being (pre-score)
SCL-90-R (somatization): M (SD)	1.52 (0.50)	1.49 (0.55)	0.76
SCL-90-R (GSI): M (SD)	1.40 (0.61)	1.40 (0.67)	0.99
SF-12 (Mental health): M (SD)	2.40 (0.63)	2.27 (0.62)	0.31
SF-12 (Physical health): M (SD)	2.64 (0.79)	2.80 (0.85)	0.32
BSS: M (SD)	5.24 (1.79)	5.61 (1.98)	0.33
Diagnoses (M.I.N.I.)
Depression (n)	34	32	0.68
Generalized anxiety disorder (n)	21	20	0.84
Personality disorder (n)	8	5	0.39
Somatoform disorder (n)	2	2	>0.99
Adjustment disorder (n)	23	24	>0.99

Note: M = mean, SD = standard deviation, n = number of participants. BSS, Beeinträchtigungs-Schwere Score; GSI, global severity index; M.I.N.I.: mini-international neuropsychiatric interview; SCL-90-R, symptom checklist-90-revised; SF-12, short form health questionnaire. Statistical comparisons by Student's t-tests or χ² tests.

Figure 2.  Mean change (pre–post difference in percent) for different measures of treatment success in the experimental and the control groups. Note: *significant group difference, p < 0.05_one-tailed, Student's t-test; error bars show SEM (Standard Error of Mean). For the short form health questionnaire (SF-12), clinical improvement is indicated by a positive difference score (increase), whereas for the SCL-90-R (GSI) and the BSS, an improvement is indicated by a negative difference score (reduction). Number of patients: experimental, n = 51; control, n = 50.