Figures & data
Table I. MABP and HR before (0 min) and after 40 min of ICV infusion of 0.9% NaCl (control), oxytocin or oxytocin receptor antagonist in conscious sham-operated rats, and rats after myocardial infarction.
Figure 1 Non-significant changes of MABP and HR from baseline under resting conditions in the sham-operated (open symbols) and infarcted (filled symbols) rats receiving ICV infusions of 0.9% NaCl (triangles), OXYANT (squares) or oxytocin (OXY, circles). The arrow indicates the start of ICV infusion. Number of rats per group: sham-operated 0.9%: n = 7; sham-operated OXY: n = 6; sham-operated OXYANT: n = 7; infarcted 0.9% NaCl: n = 8; infarcted OXY: n = 6; infarcted OXYANT: n = 6.
![Figure 1 Non-significant changes of MABP and HR from baseline under resting conditions in the sham-operated (open symbols) and infarcted (filled symbols) rats receiving ICV infusions of 0.9% NaCl (triangles), OXYANT (squares) or oxytocin (OXY, circles). The arrow indicates the start of ICV infusion. Number of rats per group: sham-operated 0.9%: n = 7; sham-operated OXY: n = 6; sham-operated OXYANT: n = 7; infarcted 0.9% NaCl: n = 8; infarcted OXY: n = 6; infarcted OXYANT: n = 6.](/cms/asset/4972aaa0-ac03-48cb-b93f-2d19c395aa8a/ists_a_368938_f0001_b.gif)
Figure 2 Representative illustrations of changes in MABP and HR after application of the air jet stressor (arrow) in the sham-operated and infarcted rats during ICV infusion of 0.9% NaCl, OXY or OXYANT. The Figure shows that (1) during infusion of 0.9% NaCl MABP and HR responses to stress are markedly greater in the infarcted than in the sham-operated rat, (2) ICV administration of OXYANT intensifies MABP and HR responses to stress in the sham-operated but not in the infarcted rat and (3) ICV administered OXY reduces MABP and HR responses to stress in the infarcted but not in the sham-operated rat.
![Figure 2 Representative illustrations of changes in MABP and HR after application of the air jet stressor (arrow) in the sham-operated and infarcted rats during ICV infusion of 0.9% NaCl, OXY or OXYANT. The Figure shows that (1) during infusion of 0.9% NaCl MABP and HR responses to stress are markedly greater in the infarcted than in the sham-operated rat, (2) ICV administration of OXYANT intensifies MABP and HR responses to stress in the sham-operated but not in the infarcted rat and (3) ICV administered OXY reduces MABP and HR responses to stress in the infarcted but not in the sham-operated rat.](/cms/asset/2c33311a-7aa4-47c4-9ebd-04e9296d82b9/ists_a_368938_f0002_b.gif)
Figure 3 Mean maximal changes of MABP and HR from baseline after application of air jet stress in the sham-operated (open columns) and infarcted (filled columns) rats receiving ICV infusions of 0.9% NaCl, OXY or OXYANT. Number of rats per group: sham-operated 0.9%: n = 7; sham-operated OXY: n = 6; sham-operated OXYANT: n = 7; infarcted 0.9% NaCl: n = 8; infarcted OXY: n = 6; infarcted OXYANT: n = 6. Asterisks indicate significant differences between the experimental groups *P < 0.05; **P < 0.01; ***P < 0.001.
![Figure 3 Mean maximal changes of MABP and HR from baseline after application of air jet stress in the sham-operated (open columns) and infarcted (filled columns) rats receiving ICV infusions of 0.9% NaCl, OXY or OXYANT. Number of rats per group: sham-operated 0.9%: n = 7; sham-operated OXY: n = 6; sham-operated OXYANT: n = 7; infarcted 0.9% NaCl: n = 8; infarcted OXY: n = 6; infarcted OXYANT: n = 6. Asterisks indicate significant differences between the experimental groups *P < 0.05; **P < 0.01; ***P < 0.001.](/cms/asset/d6f31dce-5a09-4659-8420-ff04c781bc9b/ists_a_368938_f0003_b.gif)