Figures & data
Figure 1. Basal and stress-induced plasma corticosterone concentrations after the 15, 30 min and 1 h stress procedures in the proestrus and estrus phases of the estrous cycle. Each column represents the mean ± SEM. Number of rats was set as n = 8/group. *p < 0.05 vs. control (Student–Newman–Keuls).
Figure 2. Sum of flinching and facial rubbing behaviors recorded in rats given TMJ injection of formalin (50 μl, 1.5%) previously submitted to 15, 30 min or 1 h of restraint (n = 6/group) or left undisturbed in their home cage (n = 6/group) during the estrus and proestrus phases. Each column represents the mean. Error bars indicate the SEM. +p < 0.05, estrus vs. proestrus control rats; *p < 0.05, controls vs. 1 h stressed groups; #p < 0.05, estrus vs. proestrus in 1 h stressed group (two-way ANOVA).
Figure 3. Nociceptive behavior in control (unstressed), stressed (1 h), saline-treated (+1 h stress), and nor-BNI-treated (+1 h stress) rats after formalin injection (50 μl, 1.5%) into the TMJ in estrus or proestrus phases (n = 6/group). Each column represents the mean ± SEM. *p < 0.05 vs. unstressed control rats (two-way ANOVA). #p < 0.05 estrus vs. proestrus (Tukey test). $p < 0.05, nor-BNI vs. saline and 1 h stressed groups (Tukey test).
Figure 4. Nociceptive behavior in unstressed rats in estrus or proestrus given formalin injection (50 μl, 1.5%) and nor-BNI into the TMJ. Control: formalin only, saline: saline+formalin, nor-BNI: nor-BNI+formalin; n = 6/group. Each column represents the mean ± SEM. #p < 0.05 vs. the estrus groups (two-way ANOVA).
