Figures & data
Figure 1. Drug release profiles from PDDS.
Figure 2. Classification of PDDS.
Figure 3. Scheme of the pulsed release biodegradable capsules.
Figure 4. Schematic representation of liposome-loaded alginate–poly (L-lysine). microcapsules.
Figure 5. Hypothetical design and plasma drug profile of a multi-particulate PDDS. (a) Design of a pellet with multiple coatings, (b) Predicted bi-modal plasma concentration profile.
Figure 6. Model structure of freely mobile linear PIPAAm-grafted PIPAAm hydrogels.
Figure 7. Structure of block copolymer micelles.
Figure 8. On–off release regulation of adriamycin from PIPAAm–PBMA micelles and PIPAAm–PST micelles in response to temperature switching at 4 and 40°C.
Figure 9. (a) Equilibria for alkylamidephenylboronic acid. (b) Repeated on–off release of FITC–insulin from PIPAAm–acrylamidephenylboronic acid copolymer gel beads at 28°C, pH 9.0 in response to external glucose concentration changes.
Table 1. Diseases requiring PDDS.
Table 2. Marketed technologies of PDDS.