Figures & data
Table 1. The average particle size, EE, PDI, and percentage amine group content of unlabeled gelatin nanoparticles and FITC-TT loaded GNPs and AGNPs. Values are expressed as mean ± SD (n = 3).
Figure 1. SEM image showing spherical morphology of TT loaded AGNPs
Figure 2. Cumulative % release of FITC-TT from various formulations at various time periods up to 48 h
Figure 3. Far-UV CD spectra of tetanus toxoid in acetone to water ratio of 1:3 at 40oC after 5h of incubation period.
Figure 4. Fluorescence spectra of tetanus toxoid in acetone to water ratio of 1:3 at 40oC after 5h of incubation period.
Figure 5. Serum anti-TT profile of mice immunized subcutaneously with different formulations. Values are expressed as mean±S.D. (n = 6) 55x35mm (300 × 300 DPI)
Figure 6. Log IgG1 and Log IgG2a titre of different formulations after s.c injection at 0 and 8 weeks. Values are expressed as mean±S.D. (n = 6) 177×105mm (72 × 72 DPI)
Figure 7. Gelatin and aminated gelatin specific IgG antibody response with selected formulation loaded with TT at 0 and 8 week following s.c administration. Values are expressed in terms of log10 IgG antibody titers 73 × 48mm (200 × 200 DPI)
Figure 8. Interferon-γ levels in the spleen of mice immunized with different formulations. Values are expressed as mean±S.D. (n=6) 47 × 31mm (300 × 300 DPI)
Figure 9. IL-2 level (ng/spleen) in spleenocytes supernatant at 0 and 8 weeks after s.c injection 49×32mm (300 × 300 DPI)
