Figures & data
Table 1. Composition of the CCS films.
Table 2. Evaluation of trials (mean ± SD, n = 3).
Figure 1. Release profiles of Cu B from CCS-films prepared by trial 1, trial 2, trial 3 and trial 4 (n = 6, mean ± SD).
![Figure 1. Release profiles of Cu B from CCS-films prepared by trial 1, trial 2, trial 3 and trial 4 (n = 6, mean ± SD).](/cms/asset/eb1ca996-aa68-48e9-97dc-629c37d4bf7f/idrd_a_876459_f0001_c.jpg)
Figure 2. SEM micrographs of the final formulation. The images of the peripheral and middle regions are represented on the left and right side, respectively.
![Figure 2. SEM micrographs of the final formulation. The images of the peripheral and middle regions are represented on the left and right side, respectively.](/cms/asset/8e1f7699-66c0-4002-8854-b2f9cd3cf0a3/idrd_a_876459_f0002_b.jpg)
Figure 3. Transmission electron micrographs of Cu B-PL/SDC-MMs. The images of the initial MMs solution and reconstituted MMs solution are represented on the left and right side, respectively (scale bar = 100 nm).
![Figure 3. Transmission electron micrographs of Cu B-PL/SDC-MMs. The images of the initial MMs solution and reconstituted MMs solution are represented on the left and right side, respectively (scale bar = 100 nm).](/cms/asset/fafe9c30-0f66-4afb-bb9c-369030b87de7/idrd_a_876459_f0003_b.jpg)
Table 3. MMs sizes and EE of the initial MMs solution and reconstituted MMs solution (mean ± SD, n = 3).
Figure 4. Plasma concentration-time profile of Cu B in rabbits after administration of 1 mg/kg Cu B in different formulations. Each point represents the mean ± SD of five experiments.
![Figure 4. Plasma concentration-time profile of Cu B in rabbits after administration of 1 mg/kg Cu B in different formulations. Each point represents the mean ± SD of five experiments.](/cms/asset/1ddf880f-1da1-45eb-9e52-49e1a52e9779/idrd_a_876459_f0004_c.jpg)