Figures & data
Table 1. Compositions of neomycin sulfate-loaded HDs.
Figure 1. Effect of PVP/SA ratio on the physical dressing property of neomycin sulfate-loaded HDs: (A) swelling capacity; (B) bioadhesive strength; (C) tensile strength; (D) elongation at break; and (E) Young’s modulus. The neomycin sulfate-loaded HDs were composed of PVA, PVP and SA at the weight ratio. Each value represents the mean ± SD (n = 3).
Figure 2. Effect of PVP/SA ratio on the drug release from neomycin sulfate-loaded HDs. The neomycin sulfate-loaded HDs were composed of PVA, PVP and SA at the weight ratio. Each value represents the mean ± SD (n = 6).
Figure 3. The representative images of wound model: (A) nontreated; (B) commercial product treated; (C) drug-free HD treated; (D) neomycin sulfate-loaded HD treated. The neomycin sulfate-loaded HDs were composed of drug, PVA, PVP and SA at the weight ratio of 1/10/0.8/0.8.
Figure 4. Wound-curing profile of wound model in nontreated, commercial product treated, drug-free HD treated and neomycin sulfate-loaded HD treated. The neomycin sulfate-loaded HDs were composed of drug, PVA, PVP and SA at the weight ratio of 1/10/0.8/0.8. Each value represents the mean ± SD (n = 4). *p < 0.05 and #p < 0.05 compared with nontreated and the commercial product, respectively.
Figure 5. Representative histopathological profiles: (A) nontreated; (B) commercial product-treated; (C) drug-free HD treated; (D) neomycin sulfate-loaded HD treated.
