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Research Article

The effect of polymerized placenta hemoglobin on renal ischemia/reperfusion injury

, , , , , & show all
Pages 396-399 | Received 09 Mar 2012, Accepted 18 May 2012, Published online: 15 Nov 2012

Figures & data

Figure 1. The experimental protocol of this study. I/R: ischemia/reperfusion; L-RS: Lactated Ringer's solution; HBOC: hemoglobin-based oxygen carrier.

Figure 1. The experimental protocol of this study. I/R: ischemia/reperfusion; L-RS: Lactated Ringer's solution; HBOC: hemoglobin-based oxygen carrier.

Figure 2. The SBP (A) and HR (B) before and after HBOC injection. Values were presented as mean ± SD (n = 15). HBOC: hemoglobin based oxygen carrier; HR: heart rate; L-RS: Lactated Ringer's solution; SBP: systolic blood pressure.

Figure 2. The SBP (A) and HR (B) before and after HBOC injection. Values were presented as mean ± SD (n = 15). HBOC: hemoglobin based oxygen carrier; HR: heart rate; L-RS: Lactated Ringer's solution; SBP: systolic blood pressure.

Figure 3. The releases of creatinine (A) and BUN (B) in the plasma after renal I/R injury. Values were presented as mean ± SD (n = 15). *P< 0.05 and **P< 0.01 vs. the sham group; †P< 0.05 vs. the I/R group. BUN: blood urea nitrogen.

Figure 3. The releases of creatinine (A) and BUN (B) in the plasma after renal I/R injury. Values were presented as mean ± SD (n = 15). *P< 0.05 and **P< 0.01 vs. the sham group; †P< 0.05 vs. the I/R group. BUN: blood urea nitrogen.

Figure 4. The levels of TNF-α (A) and IL-8 (B) in the renal tissue after I/R injury. Values were presented as mean ± SD (n = 15). **P< 0.01 and *P< 0.05 vs. the sham group; †P< 0.05 vs. the I/R group. TNF-α: tumor necrosis factor-α; IL-8: interleukin-8.

Figure 4. The levels of TNF-α (A) and IL-8 (B) in the renal tissue after I/R injury. Values were presented as mean ± SD (n = 15). **P< 0.01 and *P< 0.05 vs. the sham group; †P< 0.05 vs. the I/R group. TNF-α: tumor necrosis factor-α; IL-8: interleukin-8.

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