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Biomarkers Volume 18, 2013 - Issue 2
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Short Communication

Quantification of arsenic, lead, mercury and cadmium in newborn dried blood spots

William E. FunkLaboratory for Human Biology Research, Department of Anthropology, Northwestern University Evanston, ILUSACorrespondence[email protected]
,
John K. McGeeNational Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency Research Triangle Park, NCUSA
,
Andrew F. OlshanDepartment of Epidemiology, University of North Carolina Chapel Hill, NCUSA
&
Andrew J. GhioHuman Studies Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency Chapel Hill, NCUSA
Pages 174-177 | Received 05 Oct 2012, Accepted 13 Nov 2012, Published online: 12 Jan 2013
 
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Abstract

Exposures to heavy metals during fetal and perinatal development are of particular concern. Yet, the health impacts of exposures to toxic metals during these early stages of human development are not well understood due to the paucity of in vivo human data. Dried blood spots (DBS), collected by public health departments to screen for inherited metabolic errors and other disorders, are routinely archived and can be used for exposure assessment. Here we report an improved method for quantifying arsenic, lead, mercury and cadmium in newborn DBS to facilitate epidemiologic research on the health effects of early exposures to toxic metals.

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